Back to results
University of Illinois at Urbana-Champaign
Utilization of Rationally Designed Small Molecule Chiral Selectors in Novel Enantioselective Processes
Abstract
dc:descriptionIn addition, phase transfer catalyzed biphasic kinetic resolutions of several racemic amides containing electron-deficient aromatic moieties are described. The method revolves around forming Meisenheimer adducts which are stabilized by quaternary ammonium salts in a nonpolar medium. When run in the presence of a chiral selector, one enantiomer is effectively shielded from reaction. The methodology is extended to enantioselective nucleophilic aromatic substitution, reactions known to proceed through the intermediacy of a Meisenheimer adduct.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Chemical Engineering
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Snyder, Seth Elliot
- Contributors dc:contributor
-
- Pirkle, William H.
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (MiAaPQ)AAI3086180
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/82349