The Mechanism of Cap-Independent Initiation of Translation of Satellite Tobacco Necrosis Virus RNA

Satellite Tobacco Necrosis Virus RNA (STNV RNA) is an efficient, eukaryotic mRNA lacking a 5$\sp\prime$-terminal cap group or 5$\sp\prime$-terminal covalently-linked protein. Addition of a 5$\sp\prime$-terminal cap group does not enhance the translation of STNV RNA. This suggests that STNV RNA contains some feature(s) which compensates for its lack of a 5$\sp\prime$-terminal cap group. Interestingly, the 5$\sp\prime$-untranslated region of STNV RNA contains a nucleotide sequence that is complementary to the 3$\sp\prime$-terminal region of the 18S rRNA.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Biochemistry

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2014

Author dc:creator

• Schodin, David Jay

Contributors dc:contributor

• Clark, John M., Jr.

• Biology, Molecular
• Chemistry, Biochemistry

Identifier

(UMI)AAI9305684

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/72353