Static Mechanical Characteristics of the Small Collecting Vein and the First-Order Venule in the Denervated Small Intestines of the Wistar, Wistar-Kyoto, and Spontaneously Hypertensive Rats

This study was centered around two basic themes. The first related to the mechanics of the venous system, the second to venous function in hypertension. Since the venous system holds a large fraction of the total peripheral blood volume (and much of this possibly located in the venous microcirculation), and understanding of venule distention characteristics is important. In addition, veins in hypertensive animals appear to be stiffer than their controls; thus microvascular assessment of the hypertensive venous system is needed. The two hypotheses of this project were that (1) wall structure of a venule is a significant factor in determining distension characteristics during venous pressure elevation, and (2) venule wall stiffness is significantly increased in the spontaneously hypertensive rat (SHR).

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Physiology

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2014

Author dc:creator

• Lang, Douglas James

• Biology, Animal Physiology

Identifier

(UMI)AAI8409979

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/71426