Studies in molecular recognition. Part I. Expanded molecular tweezers: Design and synthesis of novel receptors. Part II. Molecular self-assembly: Use of carboxylic acids as self-assembly elements

In Part I, the design, synthetic approaches, and complexation studies of molecular tweezers possessing spacer units $>$7 A are discussed. A general feature of these approaches is the use of the Friedlander reaction to generate the spacer unit. A tweezer utilizing 2,7-dimethoxyacridine as the chromophore with an inter-chromophore distance of 9.7 A was synthesized. This expanded tweezer was found to bind 2,4,5,7-tetranitrofluorenone (TENF) with a K$\sb{\rm a}$ $<$ 10 M$\sp{-1}$. Progress in the synthesis of a water soluble tweezer with an expanded spacer unit is also reported.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Chemistry

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

1994

Author dc:creator

• Reichert, David Edward Caples

Contributors dc:contributor

• Zimmerman, Steven C.

• Chemistry, Organic

Statement dc:rights

• Copyright 1994 Reichert, David Edward Caples

Language dc:language

eng

Identifier

AAI9512525
(UMI)AAI9512525

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/22668