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University of Illinois at Urbana-Champaign

The effect of soil parameters on the bioavailability and retention of lead in rats

Abstract

dc:description

This study investigated the relationship between soil cation exchange capacity (CEC) and soil amendments (lime and phosphate) to the retention of lead in soil fed to rats. This study also related the amount of lead that can be extracted from in situ contaminated soils from a secondary smelter site to both soil properties and to the tissue lead concentrations in rats. In a six week feeding trial, 208 rats were divided into 26 groups and fed diets containing contaminated and uncontaminated soils (5% of diet) of three CEC levels that were amended with lime and/or phosphate or unamended. A soil-free negative control and lead acetate positive control group were included. Lead concentrations were measured in blood, liver, kidney, and femur. There were no significant amendment effects in the low lead soils, although there was a small CEC effect. The high lead soil groups showed no CEC effect; however, amendment type was significant and consistent across the tissues, with the lime and phosphate/lime groups generally being lower than the unamended and phosphate-amended groups. However, the total lead had more influence on the tissue values than the amendment effects. A third soil concentration (220-250 mg/kg) that did not fit into the low soil groups (40-50 mg/kg) showed a significant amendment effect for week 3 and 6 blood and femur.

Degree

thesis:*
Name thesis:degree_name
Ph.D.
Level thesis:degree_level
Dissertation
Discipline thesis:degree_discipline
Comparative Biosciences
Grantor
University of Illinois at Urbana-Champaign
Year dc:date
2011

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Malpas, Phyllis B.
Contributors dc:contributor
  • Buck, William B.

Subjects

dc:subject × 3

Rights

dc:rights
Statement dc:rights
  • Copyright 1996 Malpas, Phyllis B.
Language dc:language
eng

Identifiers

dc:identifier.*
Identifier
9780591199314
AAI9712366
(UMI)AAI9712366
OAI identifier oai:identifier
oai:www.ideals.illinois.edu:2142/22469

Chain of custody

source
Harvested from
University of Illinois - Urbana-Champaign
Base URL
www.ideals.illinois.edu/oai-pmh
Last updated
2026-07-22
Source record
OAI-PMH GetRecord
citation

Malpas, Phyllis B.. The effect of soil parameters on the bioavailability and retention of lead in rats. Dissertation thesis, University of Illinois at Urbana-Champaign, 2011. http://hdl.handle.net/2142/22469