Experimental and modeling studies of endosomal sorting using the epidermal growth factor/receptor system in fibroblasts

Receptor mediated endocytosis is the process by which cells internalize ligands which have specifically interacted with cell surface receptors. Cells have the ability to sort internalized ligands and their receptors to lysosomes for degradation, to recycle them back to the plasma membrane, or to sort ligands and receptors to separate destinations. We are interested in understanding how membrane-associated receptors are sorted within endosomes and how this process affects ligand sorting.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Chemical Engineering

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2011

Author dc:creator

• French, Anthony Raymond

• Biology, Cell
• Chemistry, Biochemistry
• Engineering, Chemical

Statement dc:rights

• Copyright 1995 French, Anthony Raymond

Language dc:language

eng

Identifier

AAI9624346
(UMI)AAI9624346

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/21969