Molecular analysis of oxygen toxicity in the obligate anaerobe Roseburia cecicola: Isolation of a compound that degrades DNA when exposed to oxygen

Environmental and nutritional conditions influence the ability of microorganisms to colonize gastrointestinal habitats. My thesis research provides a basis for examining the ecological significance of one such environmental factor, oxygen, and its effect on microbial colonization of the mammalian gastrointestinal tract. Studies described here examine how oxygen affects a bacterium isolated from the mucosa of the murine cecum, Roseburia cecicola. This organism is a strict anaerobe whose growth is inhibited when exposed to oxygen.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Microbiology

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2011

Author dc:creator

• O'Connor, Lawrence Thomas

• Biology, Microbiology

Statement dc:rights

• Copyright 1991 O'Connor, Lawrence Thomas

Language dc:language

eng

Identifier

AAI9210939
(UMI)AAI9210939

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/20568