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University of Connecticut

The Effects of High Intensity, Short Rest Resistance Exercise on Testosterone and Muscle Damage Markers in Men and Women

Abstract

dc:description.abstract

<p>High intensity, short rest protocols have become increasingly popular within the fitness industry. Such protocols can elicit extensive muscle damage and oxidative stress; thus the purpose of this study was to<strong> </strong>examine markers of muscle tissue damage and inflammation along with testosterone responses to a high intensity (75% 1RM), short rest resistance exercise protocol and sex-specific effects. Nine resistance trained men (age: 23.6 ± 3.5 years, weight: 77.8 ± 8.8 kilograms, height: 172.4 ± 4.0 cm, body fat 9.3 ± 3.3 %) and nine resistance trained women (age: 22.9 ± 2.0 years, weight: 68.6 ± 10.4 kilograms, height: 168.6 ± 9.4 cm, body fat 13.6 ± 3.3 %) participated. The protocol consisted of a descending pyramid scheme starting at 10 for three major lifts. No significant sex interactions were seen with testosterone or IL-6. There were significant sex interactions observed in myoglobin (IP) and CK (IP, +60, +24). Men demonstrated significant increases in testosterone (IP, +15), myoglobin (IP, +15, +60, +24), IL-6 (IP), and CK (IP, +60, +24). Women demonstrated significant increases in myoglobin (IP, +15, +60), IL-6 (IP), and CK (+24). There were no significant increases observed in women for testosterone. Women demonstrated a greater absolute increase in myoglobin per kilogram of fat free mass than men (+15, +60) indicating a sufficient degree of muscle damage. Both men and women demonstrated significant muscle damage with a high intensity, short rest protocol with different hormonal and immune responses, most likely mediated through differing signaling cascades.</p>

Degree

thesis:*
Name thesis:degree_name
Master of Science
Discipline thesis:degree_discipline
Kinesiology
Year dc:date.available
2012

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Heavens, Kristen R
Contributors dc:contributor
  • Carl Maresh; Jeff Volek
  • William Kraemer

Subjects

dc:subject × 8

Identifiers

dc:identifier.*
Repository record dc:identifier
https://digitalcommons.lib.uconn.edu/gs_theses/249
OAI identifier oai:identifier
oai:digitalcommons.lib.uconn.edu:gs_theses-1290

Chain of custody

source
Harvested from
University of Connecticut
Base URL
digitalcommons.lib.uconn.edu/do/oai/
Last updated
2026-07-24
Source record
OAI-PMH GetRecord
citation

Heavens, Kristen R. The Effects of High Intensity, Short Rest Resistance Exercise on Testosterone and Muscle Damage Markers in Men and Women. 2012. https://digitalcommons.lib.uconn.edu/gs_theses/249