The nature of leukocytic response to mouse mammary tumor implants in C3H/HeJ mice with and without anticoagulation

<p>Cancer is the second leading cause of death in the United States. The risk of cancer development and subsequent death from the disease increases sharply in the population over 55 years of age(1). Coagulation problems also increase with age and have been implicated in increasing the metastatic spread of cancer. Although cancer treatment has improved constantly it still remains quite toxic and improvement are needed</p><p>Mouse mammary tumor is a common form of cancer used for experimental animal study. This investigation was designed to study the nature of leukocytic response to mouse mammary tumor implants in C3H/HeJ mice with and without anticoagulants. The main thrust of the research was in three areas: first, to develop a background in light microscope morphology of spontaneous mouse mammary tumor and its change with first and second passage into normal mice; second, to analyze change in leukocytic response in sham operated, tumor- and liver-implanted mice; and third, to analyze changes in leukocytic response to tumor implants with and without anticoagulation.</p>

Name thesis:degree_name

Master of Science (M.S.)

Level thesis:degree_level

Thesis

Discipline thesis:degree_discipline

Graduate Studies

Year dc:date.available

1984

Author dc:creator

• Liter, Melvin Earl

Contributors dc:contributor

• Patrick N. Catania

• Anticoagulants (Medicine)
• Leucocytes
• Tumor antigens
• Medicine and Health Sciences

Licence

• http://rightsstatements.org/vocab/NKC/1.0/

Repository record dc:identifier

https://scholarlycommons.pacific.edu/uop_etds/472

OAI identifier oai:identifier

oai:scholarlycommons.pacific.edu:uop_etds-1471