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University of the Pacific
Analysis of the interaction between the co-chaperone p23 and the aryl hydrocarbon receptor
Abstract
dc:description.abstract<p>The aryl hydrocarbon receptor (AhR) carboxyl terminal transcriptional activation domain was cloned, purified in denatured conditions from bacteria, refolded via limited dialysis, and analyzed for proper refolding via co-immunoprecipitation with the known binding partner SRC-1. This AhR NΔ515 transactivation domain construct was used, along with amino terminal AhR deletion constructs AhR CΔ274 and AhR CΔ553, to attempt to elucidate the nature of the interaction between AhR and p23 in vitro.</p>
Degree
thesis:*- Name thesis:degree_name
- Master of Science (M.S.)
- Level thesis:degree_level
- Thesis - Pacific Access Restricted
- Discipline thesis:degree_discipline
- Biological Sciences
- Year dc:date.available
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Thompson, John D.
- Contributors dc:contributor
-
- Lisa Wrischnik
Subjects
dc:subject × 6Rights
dc:rightsIdentifiers
dc:identifier.*- Identifier
- 9781339047355
- OAI identifier oai:identifier
- oai:scholarlycommons.pacific.edu:uop_etds-1175