Back to results
University of the Pacific
Alternative splicing of the zebrafish myosin phosphatase targeting subunit, MYPT1, produces a novel isoform
Abstract
dc:description.abstract<p>Alternative splicing of the zebrafish Myosin Phosphatase Targeting Subunit, MYPT1, produces a novel isoform (TV202). TV202 and the truncated TV202Δ ere shown to form an active complex with Protein Phosphatase 1 β (PP1β) via stress fiber assay. TV202 was also shown to be localized in the cytoplasm, enriched in a paranuclear manner. TV202Δ was found the be localized inside the nucleus. It was also found that TV202 was zygotically, but not maternally, expressed during early zebrafish development via RT-PCR.</p>
Degree
thesis:*- Name thesis:degree_name
- Master of Science (M.S.)
- Level thesis:degree_level
- Thesis - Pacific Access Restricted
- Discipline thesis:degree_discipline
- Biological Sciences
- Year dc:date.available
- 2016
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Young, Kyle E.
- Contributors dc:contributor
-
- Douglas Weiser
Subjects
dc:subject × 8Rights
dc:rightsIdentifiers
dc:identifier.*- Identifier
- 9781369131536
- OAI identifier oai:identifier
- oai:scholarlycommons.pacific.edu:uop_etds-1172