Localization of trehalose synthesis and degradation in Ascaris

Tissues of Ascaris lumbricoides (variety suum), the large round worm of pigs, contain trehalose, a disaccharide composed of two molecules of glucose. Minces of various Ascaris tissues were incubated with C14glucose to determine the site of trehalose synthesis. Chromatography and radioautography were used to identify C14trehalose synthesized during the incubation period. It was found that the reproductive tissues of both male and female Ascaris possess a mechanism for trehalose synthesis. Intestinal tissue and muscle showed no capability for trehalose synthesis under conditions of the incubation. By incubation of Ascaris tissue homogenates with commercial trehalose it was found that only intestinal tissue was capable of hydrolyzing trehalose into two molecules of glucose. The significance of synthesis and degradation of trehalose is discussed with regard to the findings of previous investigations.

Name thesis:degree_name

Master of Arts

Level thesis:degree_level

Masters

Discipline thesis:degree_discipline

Natural Sciences

Grantor

Rice University

Year dc:date.issued

1963

Author dc:creator

• Feist, Carol Fay

Advisor dc:contributor.advisor

• Read, Clark P.

Statement dc:rights

• Copyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.

Language dc:language.iso

eng

Handle dc:identifier.uri

https://hdl.handle.net/1911/89238

OAI identifier oai:identifier

oai:repository.rice.edu:1911/89238