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Showing 1 to 20 of 104 for “"Trehalose"”.
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Localization of trehalose synthesis and degradation in Ascaris
… suum), the large round worm of pigs, contain trehalose, a disaccharide composed of two molecules of glucose. Minces of various Ascaris tissues were incubated with C14glucose to determine the site of trehalose synthesis. Chromatography and radioautography were used to identify C14trehalose …
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Trehalose Monomycolate Biosynthesis and Utilization in Mycobacterium tuberculosis
… transfer of mycolic acids from a single donor, trehalose monomycolate (TMM), to different acceptors located within the cell wall. Although there are three different pathways in M. tb to produce trehalose, only one, the otsAB pathway, leads to the production of TMM. Thus, inhibiting the Ag85 …
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Pharmaceutical applications and crystal structures of trehalose and its derivatives.
a-a’-Trehalose dihydrate, a-D-glucopyranosyl-a-D-glucopyranoside, is a naturally occurring sugar composed of two glucose monomers with an a-1,1-glycosidic linkage. Some plants and animals utilise trehalose to facilitate cryptobiosis (life without water), actively synthesising and storing increased …
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Hormonal Regulation of Trehalose Metabolism in the Adult Blow Fly, Phormia Regina Meig
Made available in DSpace on 2014-12-14T07:03:57Z (GMT). No. of bitstreams: 1 7708954.pdf: 3561544 bytes, checksum: 48905dcbb046ba1981c4bbb042c4ab86 (MD5) Previous issue date: 1976
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Adsorption, encapsulated solute leakage and microflow of giant vesicles during anhydrobiotic preservation in trehalose solutions
… especially when employing the disaccharide trehalose, the ultimate goal of room temperature long-term storage has thus far not been achieved -- at least in part owing to an incomplete understanding of the fundamental cellular damage mechanisms. Although there have been many studies examining …
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ATP, trehalose, glucose, and ammonium ion levels in the two cell types of Dictyostelium discoideum
… of Dictyostelium discoideum. Each compound (ATP, trehalose, glucose, and ammonium ion) was found to be present in stalk and/or spore cells. The accumulation of NH₄⁺ was interpreted as an indication of protein degradation, a source of energy in this organism. During the early stages of …
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Influence of flight activity and octopamine on hemolymph trehalose titers in Heliothis zea (Boddie) (Lepidoptera: Noctuidae)
Hemolymph trehalose concentrations of male and female Heliothis zea were quantitated by high performance thin-layer chromatography (HPTLC) at various ages and times of the day and related to flight activity. Effects of octopamine injection or stress on trehalose levels were also quantified. Flight …
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Sugar-Derived Oleogels in Cosmetics and Food Applications: a Case Study of Trehalose- and Mannitol-Based Gelators
… their application across various industries. Trehalose has been used in cosmetic products as antioxidant, skin protectant and moisturizer, while mannitol has found extensive applications in food industry. <em>We hereby present an environmentally-friendly synthetic procedure of trehalose- and …
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The functional significance of Hsp12p and trehalose in desiccation and oxidative stress in the budding yeast Saccharomyces cerevisiae
The preservation of yeast viability and vitality during storage in the desiccated state is fundamental as several industrial processes utilise this technology. The significance of the stress response protein and putative hydrophilin, Hsp 12p, was therefore examined in vivo under desiccation …
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The design and analysis of sugar-based carrier systems for the protection of nucleic acids
… thesis was to design and analyse sugar-based (trehalose, raffinose and sucrose) carrier systems for the protection of naked plasmid DNA formulations generated by spray drying. Trehalose exists in multiple crystalline anhydrous and hydrated forms and is thought to exist in two different …
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The Putative Role Of Fatty Acids In The Activation Of Trehalose Synthesis In The Fat Body Of The Cockroach Periplaneta Americana L
Hypertrehalosemic hormones produced by the corpus cardiacum increase the concentration of several fatty acids in cockroach fat body trophocytes. The phospholipase A{dollar}sb2{dollar} (PLA{dollar}sb2){dollar} activator melittin has a similar effect. The fatty acids include palmitic, stearic, oleic …
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Targeting Trehalose and Methylglucose Lipopolysaccharide Biosynthetic Pathways in M. tuberculosis - Structural and Functional Characterisation, and Early-Stage Drug Discovery of OtsA and Rv3030
… disease to eradicate. In mycobacteria, trehalose occurs as a free sugar in the cytoplasm, as well as a constituent of cellwall glycolipids, such as cord-factor, sulfolipid-1 and lipooligosaccharides. M. tuberculosis possesses two pathways for synthesis of trehalose, the OtsA-OtsB pathway …
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Biostabilization of Lipid Bilayers: Dealing with Water Stress in Embryos of Artemia franciscana
… and stabilize cell membranes. The abilities of trehalose and LEA proteins to protect liposomes of various compositions from desiccation-induced damage were evaluated by carboxyfluorescein leakage. AfrLEA2 (cytoplasmic) and AfrLEA3m (mitochondrial) were able to offset damage during drying of …
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Serum Stable Carbohydrate-Oligoethyleneamine Copolymers for Nucleic Acid Delivery
… formulations. We designed a family of trehalose-oligoethyleneamine copolymers that showed promising plasmid DNA (pDNA) transfection results in the presence of serum proteins. A diazidotrehalose monomer was copolymerized with linear oligoethyleneamines of varying length and containing …
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Effect of different disaccharides as energy supplements in tris-egg yolk semen extender on the quality of cryopreserved boer goat spermatozoa
… of three disaccharides (maltose, sucrose and trehalose) and (b) disaccharides combination (maltose and trehalose) at different concentrations using tris-egg yolk extender. For experiment 1: the study was replicated six times and was conducted in a 3 x 2 x 2 factorial arrangement with three …
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Using Fluorescent Probes to Study the Location and Interaction of Disaccharides within Lipid Bilayers
… the excess production of a disaccharide known as trehalose. Studies have focused on better understanding this organism survival mechanism in order to help aid in the preservation of biological cells. Researchers have attempted to replicate this phenomenon in vitro through a freeze-drying technique …
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Cryopreservation of pancreatic islets
… the efficacy of the non-toxic cryoprotectant trehalose in combination with (1) membrane-permeabilising biopolymers PP-50 and PP-75 to increase intracellular uptake, and (2) antioxidants MitoQ and salidroside to reduce cryopreservation-induced oxidative stress. Due to the complex architecture …
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Synthesis and Evaluation of Carbohydrate Based Cationic Polymers for siRNA Delivery and Tracking
… the degree of polymerization (n)--one containing trehalose [Tr4(n) series: Tr4(23), Tr4(55), Tr4(77)] and the other containing beta-cyclodextrin [CD4(n) series: CD4(10), CD4(26), CD4(39), CD4(143), CD4(239)]. In addition, two monosaccharide models were examined for comparison that contains …
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EFFECTS OF OSMOLYTES ON THE CONFORMATIONAL STABILITY AND HYDRODYNAMIC RADII OF IMMUNITY PROTEIN 9 AND HUMAN SERUM ALBUMIN
… in the absence and presence of osmolytes (trehalose, sucrose, and glycerol) and their effective hydrodynamic radii measured in order to further explore the mechanism of stabilisation. Urea1/2, the midpoint of the unfolding transition, and GH2O, the free energy of unfolding, were measured …
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Growth and development of the megagametophyte of the vascular plant Selaginella (Lycopsida) on defined media
… of carbon sources (glucose, sucrose, trehalose, and sorbitol), with and without B vitamins, in an attempt to induce apogamy. Without B vitamins growth was enhanced on glucose and trehalose, but not on sucrose. With B vitamins growth was enhanced on all types and concentrations of …
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