A novel method of producing microbubbles for targeted drug delivery.

Microbubbles, currently employed in diagnostic ultrasound as a contrast agent, have a potential new application as vehicles for targeted drug delivery, which could revolutionise medicine by eliminating side-effects. A new device is developed which outperforms all existing devices in terms of minimum microbubble size:channel diameter ratio. A numerical model is established to describe the flow behaviour and it is determined that the flow regime and resulting microbubble size are dependent on the ratio of inner- to outer Weber number.

Name dc:type.qualificationname

PhD

Level dc:type.qualificationlevel

Doctoral

Grantor dc:publisher.institution

Robert Gordon University

Year dc:date.issued

2016

Author dc:creator

• Fiabane, Joe

Advisor dc:contributor.advisor

• Ketan Pancholi, Paul Prentice, Iain Steel and Peter K.J. Robertson

• Microfluidics
• Microbubbles
• Drug delivery
• Jet breakup
• Turbulence
• Weber number
• CFD
• Fluent

Language dc:language

en

Identifier

oai:rgu-repository.worktribe.com:248851

OAI identifier oai:identifier

oai:rgu-repository.worktribe.com:248851