Evaluation von KIR-Liganden Inkompatibilität bei unverwandten Knochenmark-/ Stammzelltransplantationen

We performed a retrospective study in 185 patients with myelogenous leukemias who had received hematopoietic cells from unrelated donors. The aim of this study was to answer the question wether the benefit of KIR ligand incompatibility seen in haploidentical tranplantations can also be seen using unrelated donors. We could not detect a significant difference in survival between patients with a KIR ligand incompatibility and those with either fully matched or partially mismatched unrelated donors in this patient cohort.

Level thesis:degree_level

thesis.doctoral

Grantor dc:publisher

Technische Universität Dresden

Year

2005

Author dc:creator

• Martin, Hilmar

Contributors dc:contributor

• Frank, Karl-Heinz
• Suttorp, Meinolf

• KIR match
• KIR mismatch
• KIR-Liganden Inkompatibilität
• NK-Zell Alloreaktivität
• Natürliche Killer Zellen
• killer immunoglobulin like receptor
• myeloische Leukämie
• unverwandte Spender
• KIR ligand incompatibility
• natural killer cells
• nk cell alloreactivity
• unrelated donors