Epigenetic Changes in the Innate Response of Gingival Epithelium

In this study we showed TLR2 CpG promoter methylation in periodontitis affected human gingival tissues and in primary human gingival epithelial cells chronically stimulated with P. gingivalis that may instigate epithelial dysbiosis that may create a unique pathogen niche in the gingival crevice and susceptibility to periodontitis.

Author dc:creator

• Abdolhosseini, Mahsa

Advisor dc:contributor.advisor

• Denis F. Kinane, BDS, PhD

Repository record dc:identifier.uri

https://repository.upenn.edu/handle/20.500.14332/9405

OAI identifier oai:identifier

oai:repository.upenn.edu:20.500.14332/9405