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National University of Singapore

EXPLORING THE ALLOSTERIC INHIBITION MECHANISM OF HUMAN KIDNEY TYPE GLUTAMINASE TO ARREST CANCER CELL PROLIFERATION AND INVESTIGATING HAKAI MEDIATED UBIQUITINATION TOWARDS CONTROLLING CANCER CELL MIGRATION

dc:creator SARATH RAMACHANDRAN
dc:date.issued2016

Abstract

dc:description.abstract

The development and progression of cancer can be associated with certain hallmarks. Two among them are the altered cell metabolism (Warburg effect), and cancer cell invasion/progression mediated by post-translational modulation of cell signaling. In this thesis we have attempted to explore these two hallmarks towards understanding different avenues to arrest cancer cell growth

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • SARATH RAMACHANDRAN

Subjects

dc:subject × 1

Chain of custody

source
Harvested from
National University of Singapore
Base URL
scholarbank.nus.edu.sg/oai/request
Last updated
2026-07-24
Source record
OAI-PMH GetRecord
related terms
citation

SARATH RAMACHANDRAN. EXPLORING THE ALLOSTERIC INHIBITION MECHANISM OF HUMAN KIDNEY TYPE GLUTAMINASE TO ARREST CANCER CELL PROLIFERATION AND INVESTIGATING HAKAI MEDIATED UBIQUITINATION TOWARDS CONTROLLING CANCER CELL MIGRATION. 2016.

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