{"id":{"repo_id":"nus","oai_identifier":"oai:scholarbank.nus.edu.sg:10635/134571"},"canonical_url":"https://search.dev.ndltd.org/etd/nus/oai:scholarbank.nus.edu.sg:10635/134571","repository":{"repo_id":"nus","name":"National University of Singapore","base_url":"https://scholarbank.nus.edu.sg/oai/request"},"display":{"title":"EXPLORING THE ALLOSTERIC INHIBITION MECHANISM OF HUMAN KIDNEY TYPE GLUTAMINASE TO ARREST CANCER CELL PROLIFERATION AND INVESTIGATING HAKAI MEDIATED UBIQUITINATION TOWARDS CONTROLLING CANCER CELL MIGRATION","abstract":"The development and progression of cancer can be associated with certain hallmarks. Two among them are the altered cell metabolism (Warburg effect), and cancer cell invasion/progression mediated by post-translational modulation of cell signaling. In this thesis we have attempted to explore these two hallmarks towards understanding different avenues to arrest cancer cell growth","abstract_html":"The development and progression of cancer can be associated with certain hallmarks. Two among them are the altered cell metabolism (Warburg effect), and cancer cell invasion/progression mediated by post-translational modulation of cell signaling. In this thesis we have attempted to explore these two hallmarks towards understanding different avenues to arrest cancer cell growth","abstract_has_math":false,"creators":["SARATH RAMACHANDRAN"],"institution":null,"degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2016,"date_issued":"2016-01-22","date_published":"2016-01-22","updated_at":"2026-07-24T03:31:51Z","subjects":["KGA, hakai, compound 968, CB839, CBTBP"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":null,"outbound_label":null,"outbound_source":null},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["SARATH RAMACHANDRAN"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.issued","label":"Date","values":["2016-01-22"]},{"key":"dc:relation.isreferencedby","label":"Dc Relation Isreferencedby","values":["https://scholarbank.nus.edu.sg/handle/10635/134571"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["KGA, hakai, compound 968, CB839, CBTBP"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://scholarbank.nus.edu.sg/bitstreams/f0610e5b-14a5-47d0-a42a-d40caa0859a6/download"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["The development and progression of cancer can be associated with certain hallmarks. Two among them are the altered cell metabolism (Warburg effect), and cancer cell invasion/progression mediated by post-translational modulation of cell signaling. In this thesis we have attempted to explore these two hallmarks towards understanding different avenues to arrest cancer cell growth"]},{"key":"dc:format.checksum.md5","label":"Dc Format Checksum Md5","values":["83bdb7afbb57800c89f6bc578ea7f3cf","0a088959314aa6ad2df07aea35374da6"]},{"key":"dc:title","label":"Title","values":["EXPLORING THE ALLOSTERIC INHIBITION MECHANISM OF HUMAN KIDNEY TYPE GLUTAMINASE TO ARREST CANCER CELL PROLIFERATION AND INVESTIGATING HAKAI MEDIATED UBIQUITINATION TOWARDS CONTROLLING CANCER CELL MIGRATION"]}]}],"canonical_facts":{"dc:creator":["SARATH RAMACHANDRAN"],"dc:date.issued":["2016-01-22"],"dc:description.abstract":["The development and progression of cancer can be associated with certain hallmarks. Two among them are the altered cell metabolism (Warburg effect), and cancer cell invasion/progression mediated by post-translational modulation of cell signaling. In this thesis we have attempted to explore these two hallmarks towards understanding different avenues to arrest cancer cell growth"],"dc:format.checksum.md5":["83bdb7afbb57800c89f6bc578ea7f3cf","0a088959314aa6ad2df07aea35374da6"],"dc:identifier.uri":["https://scholarbank.nus.edu.sg/bitstreams/f0610e5b-14a5-47d0-a42a-d40caa0859a6/download"],"dc:relation.isreferencedby":["https://scholarbank.nus.edu.sg/handle/10635/134571"],"dc:subject":["KGA, hakai, compound 968, CB839, CBTBP"],"dc:title":["EXPLORING THE ALLOSTERIC INHIBITION MECHANISM OF HUMAN KIDNEY TYPE GLUTAMINASE TO ARREST CANCER CELL PROLIFERATION AND INVESTIGATING HAKAI MEDIATED UBIQUITINATION TOWARDS CONTROLLING CANCER CELL MIGRATION"],"dc:type":["Thesis"]},"updated_at":"2026-07-24T03:31:51Z"}