Orally Induced Tolerance to Streptococcus Mutans and Glucosyltransferase in Neonatal Mice

Three antigens, glucosyltransferase (GTase), formalin killed Streptococcus mutans cells (vaccine) and bovine serum albumin (BSA), were used to orally induce tolerance in neonatal C57BL mice. Radial immunodiffusion was used to measure the antibody response to vaccine and BSA, and an enzyme inhibition assay was employed to measure GTase antibody titer. Daily feeding during the first eight days of life resulted in a lower antibody response to the antigens upon subsequent challenge.

Name thesis:degree_name

Master of Science in Biology

Level thesis:degree_level

Masters

Discipline thesis:degree_discipline

Biology

Year

1981

Author dc:creator

• Sterner, Kay Ellen

Contributors dc:contributor

• Richard Myers

• Biology

Statement dc:rights

• © Kay Ellen Sterner

Repository record dc:identifier

https://bearworks.missouristate.edu/theses/629

OAI identifier oai:identifier

oai:bearworks.missouristate.edu:theses-1630