{"id":{"repo_id":"mo-state","oai_identifier":"oai:bearworks.missouristate.edu:theses-1630"},"canonical_url":"https://search.dev.ndltd.org/etd/mo-state/oai:bearworks.missouristate.edu:theses-1630","repository":{"repo_id":"mo-state","name":"Missouri State University","base_url":"https://bearworks.missouristate.edu/do/oai/"},"display":{"title":"Orally Induced Tolerance to Streptococcus Mutans and Glucosyltransferase in Neonatal Mice","abstract":"Three antigens, glucosyltransferase (GTase), formalin killed Streptococcus mutans cells (vaccine) and bovine serum albumin (BSA), were used to orally induce tolerance in neonatal C57BL mice. Radial immunodiffusion was used to measure the antibody response to vaccine and BSA, and an enzyme inhibition assay was employed to measure GTase antibody titer. Daily feeding during the first eight days of life resulted in a lower antibody response to the antigens upon subsequent challenge.","abstract_html":"Three antigens, glucosyltransferase (GTase), formalin killed Streptococcus mutans cells (vaccine) and bovine serum albumin (BSA), were used to orally induce tolerance in neonatal C57BL mice. Radial immunodiffusion was used to measure the antibody response to vaccine and BSA, and an enzyme inhibition assay was employed to measure GTase antibody titer. Daily feeding during the first eight days of life resulted in a lower antibody response to the antigens upon subsequent challenge.","abstract_has_math":false,"creators":["Sterner, Kay Ellen"],"institution":null,"degree_name":"Master of Science in Biology","degree_level":"Masters","degree_discipline":"Biology","degree_department":null,"school":null,"contributors":["Richard Myers"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1981,"date_issued":"1981-05-01T07:00:00Z","date_published":"1981-05-01T07:00:00Z","updated_at":"2026-07-24T03:15:42Z","subjects":["Biology"],"languages":[],"rights":["© Kay Ellen Sterner"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://bearworks.missouristate.edu/theses/629","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Richard Myers"]},{"key":"dc:creator","label":"Author","values":["Sterner, Kay Ellen"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"thesis:degree_discipline","label":"Discipline","values":["Biology"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Masters"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science in Biology"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Biology"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:rights","label":"Dc Rights","values":["© Kay Ellen Sterner"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://bearworks.missouristate.edu/theses/629"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Three antigens, glucosyltransferase (GTase), formalin killed Streptococcus mutans cells (vaccine) and bovine serum albumin (BSA), were used to orally induce tolerance in neonatal C57BL mice. Radial immunodiffusion was used to measure the antibody response to vaccine and BSA, and an enzyme inhibition assay was employed to measure GTase antibody titer. Daily feeding during the first eight days of life resulted in a lower antibody response to the antigens upon subsequent challenge."]},{"key":"dc:title","label":"Title","values":["Orally Induced Tolerance to Streptococcus Mutans and Glucosyltransferase in Neonatal Mice"]}]}],"canonical_facts":{"dc:contributor":["Richard Myers"],"dc:creator":["Sterner, Kay Ellen"],"dc:description.abstract":["Three antigens, glucosyltransferase (GTase), formalin killed Streptococcus mutans cells (vaccine) and bovine serum albumin (BSA), were used to orally induce tolerance in neonatal C57BL mice. Radial immunodiffusion was used to measure the antibody response to vaccine and BSA, and an enzyme inhibition assay was employed to measure GTase antibody titer. Daily feeding during the first eight days of life resulted in a lower antibody response to the antigens upon subsequent challenge."],"dc:identifier":["https://bearworks.missouristate.edu/theses/629"],"dc:rights":["© Kay Ellen Sterner"],"dc:subject":["Biology"],"dc:title":["Orally Induced Tolerance to Streptococcus Mutans and Glucosyltransferase in Neonatal Mice"],"thesis:degree_discipline":["Biology"],"thesis:degree_level":["Masters"],"thesis:degree_name":["Master of Science in Biology"]},"updated_at":"2026-07-24T03:15:42Z"}