Study of 4(E)-Trans-6, 7-Epoxy-2, 2-Dimethyl-4-Decen-3-One

Hepoxilins are a group of compounds which are biologically active in the body. One of the hepoxilins is vital in the release of insulin. The sites that metabolism chemistry of the hepoxilin molecule takes place will be investigated using a model compound. The model compound, 4(E)-trans-6,7-epoxy-2,2-dimethly-4-decen-3-one, will be synthesized using a Witting reaction. Molecular orbital calculations will be performed to predict reactivity, infrared spectra, and optimized structure. The phosphoranylidene used will by synthesized by reacting 1-bromo-3,3-dimethyl-2-butanone with triphenylphosphine. Then the reactive sities will be tested using phenyllithium.

Name thesis:degree_name

Master of Science in Chemistry

Level thesis:degree_level

Masters

Discipline thesis:degree_discipline

Chemistry and Biochemistry

Year

1998

Author dc:creator

• Christie, Lance Christopher

Contributors dc:contributor

• Tamera Jahnke

• Chemistry

Statement dc:rights

• © Lance Christopher Christie

Repository record dc:identifier

https://bearworks.missouristate.edu/theses/361

OAI identifier oai:identifier

oai:bearworks.missouristate.edu:theses-1362