An Evaluation of Two Interleukin-1 Assays

Interleukin-1 (IL-1) is produced by macrophages and has been shown to be an important protein involved in the regulation of an immune response. Several methods of detecting IL-1 in the supernatant of macrophage cultures have been developed. The purpose of this project was to evaluate two of these methods. The two assays used were based on the fact that T cells proliferate in the presence of IL-1 and plant lectins. These assays differed with respect to the source of the T cells: nylon wool purified or D10.G4.1 cell line. Methods involving the use of D10.G4.1 cells were founds to be more accurate than methods involving the use of nylon wool purified T cells.

Name thesis:degree_name

Master of Science in Biology

Level thesis:degree_level

Masters

Discipline thesis:degree_discipline

Biology

Year

1989

Author dc:creator

• DiVincenzo, Frank Anthony

Contributors dc:contributor

• Richard Myers

• Biology

Statement dc:rights

• © Frank Anthony DiVincenzo

Repository record dc:identifier

https://bearworks.missouristate.edu/theses/143

OAI identifier oai:identifier

oai:bearworks.missouristate.edu:theses-1144