{"id":{"repo_id":"mo-state","oai_identifier":"oai:bearworks.missouristate.edu:theses-1144"},"canonical_url":"https://search.dev.ndltd.org/etd/mo-state/oai:bearworks.missouristate.edu:theses-1144","repository":{"repo_id":"mo-state","name":"Missouri State University","base_url":"https://bearworks.missouristate.edu/do/oai/"},"display":{"title":"An Evaluation of Two Interleukin-1 Assays","abstract":"Interleukin-1 (IL-1) is produced by macrophages and has been shown to be an important protein involved in the regulation of an immune response. Several methods of detecting IL-1 in the supernatant of macrophage cultures have been developed. The purpose of this project was to evaluate two of these methods. The two assays used were based on the fact that T cells proliferate in the presence of IL-1 and plant lectins. These assays differed with respect to the source of the T cells: nylon wool purified or D10.G4.1 cell line. Methods involving the use of D10.G4.1 cells were founds to be more accurate than methods involving the use of nylon wool purified T cells.","abstract_html":"Interleukin-1 (IL-1) is produced by macrophages and has been shown to be an important protein involved in the regulation of an immune response. Several methods of detecting IL-1 in the supernatant of macrophage cultures have been developed. The purpose of this project was to evaluate two of these methods. The two assays used were based on the fact that T cells proliferate in the presence of IL-1 and plant lectins. These assays differed with respect to the source of the T cells: nylon wool purified or D10.G4.1 cell line. Methods involving the use of D10.G4.1 cells were founds to be more accurate than methods involving the use of nylon wool purified T cells.","abstract_has_math":false,"creators":["DiVincenzo, Frank Anthony"],"institution":null,"degree_name":"Master of Science in Biology","degree_level":"Masters","degree_discipline":"Biology","degree_department":null,"school":null,"contributors":["Richard Myers"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1989,"date_issued":"1989-07-01T07:00:00Z","date_published":"1989-07-01T07:00:00Z","updated_at":"2026-07-24T03:15:12Z","subjects":["Biology"],"languages":[],"rights":["© Frank Anthony DiVincenzo"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://bearworks.missouristate.edu/theses/143","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Richard Myers"]},{"key":"dc:creator","label":"Author","values":["DiVincenzo, Frank Anthony"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"thesis:degree_discipline","label":"Discipline","values":["Biology"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Masters"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science in Biology"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Biology"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:rights","label":"Dc Rights","values":["© Frank Anthony DiVincenzo"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://bearworks.missouristate.edu/theses/143"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Interleukin-1 (IL-1) is produced by macrophages and has been shown to be an important protein involved in the regulation of an immune response. Several methods of detecting IL-1 in the supernatant of macrophage cultures have been developed. The purpose of this project was to evaluate two of these methods. The two assays used were based on the fact that T cells proliferate in the presence of IL-1 and plant lectins. These assays differed with respect to the source of the T cells: nylon wool purified or D10.G4.1 cell line. Methods involving the use of D10.G4.1 cells were founds to be more accurate than methods involving the use of nylon wool purified T cells."]},{"key":"dc:title","label":"Title","values":["An Evaluation of Two Interleukin-1 Assays"]}]}],"canonical_facts":{"dc:contributor":["Richard Myers"],"dc:creator":["DiVincenzo, Frank Anthony"],"dc:description.abstract":["Interleukin-1 (IL-1) is produced by macrophages and has been shown to be an important protein involved in the regulation of an immune response. Several methods of detecting IL-1 in the supernatant of macrophage cultures have been developed. The purpose of this project was to evaluate two of these methods. The two assays used were based on the fact that T cells proliferate in the presence of IL-1 and plant lectins. These assays differed with respect to the source of the T cells: nylon wool purified or D10.G4.1 cell line. Methods involving the use of D10.G4.1 cells were founds to be more accurate than methods involving the use of nylon wool purified T cells."],"dc:identifier":["https://bearworks.missouristate.edu/theses/143"],"dc:rights":["© Frank Anthony DiVincenzo"],"dc:subject":["Biology"],"dc:title":["An Evaluation of Two Interleukin-1 Assays"],"thesis:degree_discipline":["Biology"],"thesis:degree_level":["Masters"],"thesis:degree_name":["Master of Science in Biology"]},"updated_at":"2026-07-24T03:15:12Z"}