Fiber inspired neural probes

Limitations in the currently available technology for neural probes impede our progress towards a comprehensive brain activity map. The lack of understanding the brain function leads to limited options for the treatment of neurological disorders. In this thesis, I employed a two-step thermal drawing process (TDP), widely used in fabrication of optical fibers, to create arrays of metal microelectrodes embedded in a polymer cladding. The pitch and size of the electrodes were determined on the macroscale and preserved during the TDP. I have applied these fiber-inspired probes to record spontaneous and stimulated neural activity in vivo.

Department dc:contributor.department

Massachusetts Institute of Technology. Department of Materials Science and Engineering.

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2013

Author dc:creator

• Canales, Andrés

Advisor dc:contributor.advisor

• Polina Anikeeva.

• Materials Science and Engineering.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/88380

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/88380