Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 89 for “"Microelectrodes"”.
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Mercury Amalgam Electrodeposition on Metal Microelectrodes
Mercury amalgam microelectrodes, typically fabricated by electrodeposition of mercury onto metal (platinum, gold, silver) inlaid disks, possess certain advantageous properties for scanning electrochemical microscopy (SECM) and electroanalysis. But as applications require more and more precision, …
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Double Pulse Coulometry for Interfacial Biosensing at Platinum Microelectrodes
… scheme for cholesterol sensing at platinum microelectrodes was developed and optimized to avoid amperometric measurements needed to reference to a nonzero solution baseline current and baseline shift upon repositioning the electrode in approaching and contacting with the cell plasma …
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Device design factors for enhancing the functionality of chronic intracortical microelectrodes
<p>Intracortical microelectrodes are devices used in brain-computer interfaces (BCI) to help regain lost motor, sensory, and cognitive functions of individuals with neurological disorders. However, the long-term performance of microelectrode arrays is hampered by a series of inflammatory tissue …
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Effects of Dip-coated films on the Properties of Implantable Intracortical Microelectrodes
… clinical use of implantable intracortical microelectrodes (ICMs) to treat certain types of deafness, blindness, and paralysis is limited by a reactive tissue response (RTR) of the brain. This RTR culminates in the formation of a tight glial scar and a loss of neuronal density around …
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Thiophene Derivative Monomers Co-electropolymerized on Microelectrodes within Arrays for Tailored Surface Chemistry and Electrochemical Properties
<p>Potentiodynamic co-electropolymerization of two thiophene derivatives, (2,3-dihydrothieno[3,4-b]dioxin-2-yl)methanol (1) and 4-((2,3-dihydrothieno[3,4-b][1,4]dioxin-2-yl)-methoxy)-4-oxobutanoic acid (2), in aqueous solutions (0.02 M total monomer, 0.05 M sodium dodecyl sulfate (SDS) and 0.1 M …
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Design and fabrication of a microneedle for the implantation of floating microstimulators
… components associated with the nervous system. Microelectrodes have been used in stimulating and detecting electrical activity in neurons. When stimulating or recording neural tissue activity using microelectrodes, there are usually many problems and difficulties in obtaining the correct …
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Electrochemical Analysis of Oxidation of Primary Amines to Ketones with 3,5-Di-Tert-Butyl-1,2Benzoquinone
… and voltammetric techniques. The use of microelectrodes, instead of traditional disk electrodes, allowed access to the bulk concentrations of electroactive species while minimizing electrode reactions and the effect of the diffusion layer. The first chapter of this thesis discusses the …
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Studies Toward the Development of a Microelectrode Array for Detection of Dopamine Through Redox Cycling
… electrodes. Two or more individually-addressable microelectrodes located close to each other allow redox cycling to be possible. Electrochemical behavior of a biologically important molecule, dopamine is examined under redox cycling conditions. To our knowledge, this is the first report on …
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Flexible sensors for high-quality recording and human-computer interface
… we can reduce the impedance of flexible Pt microelectrodes by 5-9-fold and reduce the thermal noise from both in vitro and in vivo recording. We also demonstrated that in addition to the surface area, the shape also affects the total impedance. We then further investigated how the design and …
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Monitoring single heart cell biology using lab-on-a- chip technologies
… platform based on five individually addressable microelectrodes, fully integrated within a microfluidic system, where the cell is electrically stimulated at pre-determined rates and real-time ionic and metabolic fluxes from active, beating single heart cells are measured. The device is comprised …
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Characterisation of electrode microarrays produced photolithographically and with thiol self-assembled monolayers on gold electrodes
… qualitative advantages. The great advantage of microelectrodes over macroelectrodes is the minimisation of interference, which gives rise to much lower detection limits. Microelectrodes have much reduced ohmic drops and capacitive effects and can be used in the absence of supporting electrolyte. …
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Mechanistic Electrochemistry: Investigations of Electrocatalytic Mechanisms for H2S Detection Applications
… FTACV measurements carried out using macro and microelectrodes in stagnant and fluidic conditions are reported for the first time. The novel strategy adopts the use of an electrocatalytic (EC') mechanism by using a redox mediator to facilitate the reaction with sulphide in aqueous solutions. In …
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Long-term characterization of the chronic dopamine microelectrode and effect of electrical conditioning
… of polyimide fused silica-encased FSCV microelectrodes have made the technique more suitable for chronic DA monitoring (months) in vivo. Methods: In this study, electrically stimulated DA signals were evoked weekly in an effort to characterize the recovery time and stability of DA …
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Mechanism of oxygen reduction reaction on transition metal oxide catalysts for high temperature fuel cells
… approach used here involves dense and thin-film microelectrodes of Lao.sSr0.2M03-d (M = Mn and Fe) supported on thin film 8YSZ electrolyte that was fabricated via microfabrication/photolithography techniques. These microelectrodes were then probed mainly via electrochemical impedance spectroscopy …
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Bioimpedance spectroscopy of breast cancer cells: A microsystems approach
… other was a microfluidic device with integrated microelectrodes to examine the biophysical properties of single cells. Second, we examined a panel of triple negative breast cancer (TNBC) cell lines and a hormone therapy resistant model of breast cancer in order to improve our understanding of the …
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Technologies for tissue culture electrophysiologic recording
… preparation that would produce consistent glass microelectrodes meeting the peculiar needs of tissue culture electrophysiology.; (6) Design of a culture recording chamber which would permit: (a) culturing of cells using standard tissue culture techniques.; (b) easy access of cells for …
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Fiber inspired neural probes
… of optical fibers, to create arrays of metal microelectrodes embedded in a polymer cladding. The pitch and size of the electrodes were determined on the macroscale and preserved during the TDP. I have applied these fiber-inspired probes to record spontaneous and stimulated neural activity in …
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Conducting polymer hydrogels for the release of glutamate and sensing of extracellular action potentials
… a CPH for drug delivery, and a CPH for coating microelectrodes. Methods: A stability indicating high performance liquid chromatography (HPLC) method was developed for the quantification of Glu from forced degradation samples and following release from CPs and CPHs. This analytical method was …
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