Effects of calcium carbonate particulate releasing surgical anchors on bone and tendon healing

The Calaxo ® screw, developed by Smith and Nephew, is a novel biomedical composite composed of poly-DL-lactide-co-glycolide (PLLA:PGA) 85:15 and calcium carbonate particulates. Comparisons to an identical surgical anchor composed of PLLA, largely considered an industry standard, shows increased mean failure strength in surgical reconstructions of the patellar-tibia complex in sheep. SEM imaging confirms the osteoconductivity of the Calaxo ® screw proposed in previous studies and also suggest a positive effect on the differentiation of tissues along the tendon-bone interface. These findings support the intended use of the Calaxo ® screw as a fixation device for rotator cuff repair procedures.

Department dc:contributor.department

Massachusetts Institute of Technology. Dept. of Materials Science and Engineering.

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2007

Author dc:creator

• Medeiros, Jordan-Ryan J. I. K

Advisor dc:contributor.advisor

• Linn W. Hobbs.

• Materials Science and Engineering.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/57971

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/57971