{"id":{"repo_id":"mit","oai_identifier":"oai:dspace.mit.edu:1721.1/57971"},"canonical_url":"https://search.dev.ndltd.org/etd/mit/oai:dspace.mit.edu:1721.1/57971","repository":{"repo_id":"mit","name":"MIT","base_url":"https://dspace.mit.edu/oai/request"},"display":{"title":"Effects of calcium carbonate particulate releasing surgical anchors on bone and tendon healing","abstract":"The Calaxo ® screw, developed by Smith and Nephew, is a novel biomedical composite composed of poly-DL-lactide-co-glycolide (PLLA:PGA) 85:15 and calcium carbonate particulates. Comparisons to an identical surgical anchor composed of PLLA, largely considered an industry standard, shows increased mean failure strength in surgical reconstructions of the patellar-tibia complex in sheep. SEM imaging confirms the osteoconductivity of the Calaxo ® screw proposed in previous studies and also suggest a positive effect on the differentiation of tissues along the tendon-bone interface. These findings support the intended use of the Calaxo ® screw as a fixation device for rotator cuff repair procedures.","abstract_html":"The Calaxo ® screw, developed by Smith and Nephew, is a novel biomedical composite composed of poly-DL-lactide-co-glycolide (PLLA:PGA) 85:15 and calcium carbonate particulates. Comparisons to an identical surgical anchor composed of PLLA, largely considered an industry standard, shows increased mean failure strength in surgical reconstructions of the patellar-tibia complex in sheep. SEM imaging confirms the osteoconductivity of the Calaxo ® screw proposed in previous studies and also suggest a positive effect on the differentiation of tissues along the tendon-bone interface. These findings support the intended use of the Calaxo ® screw as a fixation device for rotator cuff repair procedures.","abstract_has_math":false,"creators":["Medeiros, Jordan-Ryan J. I. K"],"institution":"Massachusetts Institute of Technology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":"Massachusetts Institute of Technology. Dept. of Materials Science and Engineering.","school":null,"contributors":[],"advisors":["Linn W. Hobbs."],"committee_chairs":[],"committee_members":[],"year":2007,"date_issued":"2007","date_published":"2007","updated_at":"2026-07-22T22:22:14Z","subjects":["Materials Science and Engineering."],"languages":["eng"],"rights":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 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Comparisons to an identical surgical anchor composed of PLLA, largely considered an industry standard, shows increased mean failure strength in surgical reconstructions of the patellar-tibia complex in sheep. SEM imaging confirms the osteoconductivity of the Calaxo ® screw proposed in previous studies and also suggest a positive effect on the differentiation of tissues along the tendon-bone interface. These findings support the intended use of the Calaxo ® screw as a fixation device for rotator cuff repair procedures."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["S.B."]},{"key":"dc:title","label":"Title","values":["Effects of calcium carbonate particulate releasing surgical anchors on bone and tendon healing"]}]}],"canonical_facts":{"dc:contributor.advisor":["Linn W. Hobbs."],"dc:contributor.department":["Massachusetts Institute of Technology. Dept. of Materials Science and Engineering."],"dc:contributor.other":["Massachusetts Institute of Technology. Dept. of Materials Science and Engineering."],"dc:creator":["Medeiros, Jordan-Ryan J. I. K"],"dc:date.accessioned":["2010-09-01T13:36:05Z"],"dc:date.available":["2010-09-01T13:36:05Z"],"dc:date.issued":["2007"],"dc:description":["Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2007.","Cataloged from PDF version of thesis.","Includes bibliographical references (p. 31-32)."],"dc:description.abstract":["The Calaxo ® screw, developed by Smith and Nephew, is a novel biomedical composite composed of poly-DL-lactide-co-glycolide (PLLA:PGA) 85:15 and calcium carbonate particulates. Comparisons to an identical surgical anchor composed of PLLA, largely considered an industry standard, shows increased mean failure strength in surgical reconstructions of the patellar-tibia complex in sheep. SEM imaging confirms the osteoconductivity of the Calaxo ® screw proposed in previous studies and also suggest a positive effect on the differentiation of tissues along the tendon-bone interface. These findings support the intended use of the Calaxo ® screw as a fixation device for rotator cuff repair procedures."],"dc:description.degree":["S.B."],"dc:identifier.uri":["http://hdl.handle.net/1721.1/57971"],"dc:language.iso":["eng"],"dc:publisher":["Massachusetts Institute of Technology"],"dc:rights":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 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