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Massachusetts Institute of Technology

Improving energy efficiency in a pharmaceutical manufacturing environment -- production facility

Abstract

dc:description.abstract

The manufacturing plant of a pharmaceutical company in Singapore had low energy efficiency in both its office buildings and production facilities. Heating, Ventilation and Air-Conditioning (HVAC) system was identified to be the major energy consumer in the plant. An HVAC specific energy management tool was developed to monitor the energy efficiency and calculate the heat gains and cooling loads. In the office building, the HVAC operation schedule was revised, and motion detection lighting control was installed and configured to save electricity. In production facilities, house vacuum, process vacuum and dust collector were shut down during non-production time in Pharmaceutical Facility 2 (PF2). Statistical analysis using measured data was performed to verify the projected energy savings. Dehumidifier was disabled in Pharmaceutical Facility 1 (PF1) to relax the relative humidity from around 22% to 50%, while still maintaining it within the upper specification of 55%. Theoretical AHU-Dehumidifier models were built to find the optimum system settings with minimum energy consumption. With the implemented strategies, the annual energy consumption would be reduced by 6.68%, 6.58% and 2.32% in the office building, PF1 and PF2 respectively. The AHU-Dehumidifier models suggested a pre-cooling off-coil temperature of 15.50 C and a post-cooling off-coil temperature of 21 'C in face of the current humidity requirement to achieve minimum energy consumption.

Degree

thesis:*
Department dc:contributor.department
Massachusetts Institute of Technology. Dept. of Mechanical Engineering.
Grantor dc:publisher
Massachusetts Institute of Technology
Year dc:date.issued
2009

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Zhang, Endong, M. Eng. Massachusetts Institute of Technology
Advisor dc:contributor.advisor
  • Duane S. Boning.

Subjects

dc:subject × 1

Rights

dc:rights
Statement dc:rights
  • M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.
Language dc:language.iso
eng

Identifiers

dc:identifier.*
Handle dc:identifier.uri
http://hdl.handle.net/1721.1/55235
OAI identifier oai:identifier
oai:dspace.mit.edu:1721.1/55235

Chain of custody

source
Harvested from
MIT
Base URL
dspace.mit.edu/oai/request
Last updated
2026-07-22
Source record
OAI-PMH GetRecord
citation

Zhang, Endong, M. Eng. Massachusetts Institute of Technology. Improving energy efficiency in a pharmaceutical manufacturing environment -- production facility. Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/55235