{"id":{"repo_id":"mit","oai_identifier":"oai:dspace.mit.edu:1721.1/55235"},"canonical_url":"https://search.dev.ndltd.org/etd/mit/oai:dspace.mit.edu:1721.1/55235","repository":{"repo_id":"mit","name":"MIT","base_url":"https://dspace.mit.edu/oai/request"},"display":{"title":"Improving energy efficiency in a pharmaceutical manufacturing environment -- production facility","abstract":"The manufacturing plant of a pharmaceutical company in Singapore had low energy efficiency in both its office buildings and production facilities. Heating, Ventilation and Air-Conditioning (HVAC) system was identified to be the major energy consumer in the plant. An HVAC specific energy management tool was developed to monitor the energy efficiency and calculate the heat gains and cooling loads. In the office building, the HVAC operation schedule was revised, and motion detection lighting control was installed and configured to save electricity. In production facilities, house vacuum, process vacuum and dust collector were shut down during non-production time in Pharmaceutical Facility 2 (PF2). Statistical analysis using measured data was performed to verify the projected energy savings. Dehumidifier was disabled in Pharmaceutical Facility 1 (PF1) to relax the relative humidity from around 22% to 50%, while still maintaining it within the upper specification of 55%. Theoretical AHU-Dehumidifier models were built to find the optimum system settings with minimum energy consumption. With the implemented strategies, the annual energy consumption would be reduced by 6.68%, 6.58% and 2.32% in the office building, PF1 and PF2 respectively. The AHU-Dehumidifier models suggested a pre-cooling off-coil temperature of 15.50 C and a post-cooling off-coil temperature of 21 'C in face of the current humidity requirement to achieve minimum energy consumption.","abstract_html":"The manufacturing plant of a pharmaceutical company in Singapore had low energy efficiency in both its office buildings and production facilities. Heating, Ventilation and Air-Conditioning (HVAC) system was identified to be the major energy consumer in the plant. An HVAC specific energy management tool was developed to monitor the energy efficiency and calculate the heat gains and cooling loads. In the office building, the HVAC operation schedule was revised, and motion detection lighting control was installed and configured to save electricity. In production facilities, house vacuum, process vacuum and dust collector were shut down during non-production time in Pharmaceutical Facility 2 (PF2). Statistical analysis using measured data was performed to verify the projected energy savings. Dehumidifier was disabled in Pharmaceutical Facility 1 (PF1) to relax the relative humidity from around 22% to 50%, while still maintaining it within the upper specification of 55%. Theoretical AHU-Dehumidifier models were built to find the optimum system settings with minimum energy consumption. With the implemented strategies, the annual energy consumption would be reduced by 6.68%, 6.58% and 2.32% in the office building, PF1 and PF2 respectively. The AHU-Dehumidifier models suggested a pre-cooling off-coil temperature of 15.50 C and a post-cooling off-coil temperature of 21 'C in face of the current humidity requirement to achieve minimum energy consumption.","abstract_has_math":false,"creators":["Zhang, Endong, M. Eng. Massachusetts Institute of Technology"],"institution":"Massachusetts Institute of Technology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":"Massachusetts Institute of Technology. Dept. of Mechanical Engineering.","school":null,"contributors":[],"advisors":["Duane S. Boning."],"committee_chairs":[],"committee_members":[],"year":2009,"date_issued":"2009","date_published":"2009","updated_at":"2026-07-22T22:22:09Z","subjects":["Mechanical Engineering."],"languages":["eng"],"rights":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 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Heating, Ventilation and Air-Conditioning (HVAC) system was identified to be the major energy consumer in the plant. An HVAC specific energy management tool was developed to monitor the energy efficiency and calculate the heat gains and cooling loads. In the office building, the HVAC operation schedule was revised, and motion detection lighting control was installed and configured to save electricity. In production facilities, house vacuum, process vacuum and dust collector were shut down during non-production time in Pharmaceutical Facility 2 (PF2). Statistical analysis using measured data was performed to verify the projected energy savings. Dehumidifier was disabled in Pharmaceutical Facility 1 (PF1) to relax the relative humidity from around 22% to 50%, while still maintaining it within the upper specification of 55%. Theoretical AHU-Dehumidifier models were built to find the optimum system settings with minimum energy consumption. With the implemented strategies, the annual energy consumption would be reduced by 6.68%, 6.58% and 2.32% in the office building, PF1 and PF2 respectively. The AHU-Dehumidifier models suggested a pre-cooling off-coil temperature of 15.50 C and a post-cooling off-coil temperature of 21 'C in face of the current humidity requirement to achieve minimum energy consumption."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["M.Eng."]},{"key":"dc:title","label":"Title","values":["Improving energy efficiency in a pharmaceutical manufacturing environment -- production facility"]}]}],"canonical_facts":{"dc:contributor.advisor":["Duane S. Boning."],"dc:contributor.department":["Massachusetts Institute of Technology. Dept. of Mechanical Engineering."],"dc:contributor.other":["Massachusetts Institute of Technology. Dept. of Mechanical Engineering."],"dc:creator":["Zhang, Endong, M. Eng. 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In production facilities, house vacuum, process vacuum and dust collector were shut down during non-production time in Pharmaceutical Facility 2 (PF2). Statistical analysis using measured data was performed to verify the projected energy savings. Dehumidifier was disabled in Pharmaceutical Facility 1 (PF1) to relax the relative humidity from around 22% to 50%, while still maintaining it within the upper specification of 55%. Theoretical AHU-Dehumidifier models were built to find the optimum system settings with minimum energy consumption. With the implemented strategies, the annual energy consumption would be reduced by 6.68%, 6.58% and 2.32% in the office building, PF1 and PF2 respectively. The AHU-Dehumidifier models suggested a pre-cooling off-coil temperature of 15.50 C and a post-cooling off-coil temperature of 21 'C in face of the current humidity requirement to achieve minimum energy consumption."],"dc:description.degree":["M.Eng."],"dc:identifier.uri":["http://hdl.handle.net/1721.1/55235"],"dc:language.iso":["eng"],"dc:publisher":["Massachusetts Institute of Technology"],"dc:rights":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission."],"dc:rights.uri":["http://dspace.mit.edu/handle/1721.1/7582"],"dc:subject":["Mechanical Engineering."],"dc:title":["Improving energy efficiency in a pharmaceutical manufacturing environment -- production facility"],"dc:type":["Thesis"]},"updated_at":"2026-07-22T22:22:09Z"}