Evaluation of monolayer protected metal nanoparticle technology

Self assembling nanostructured nanoparticles represent a new class of synthesized materials with unique functionality. Such monolayer protected metal nanoparticles are capable of resisting protein adsorption, and if utilized as a coating could have broad application in a wide range of industries from consumer products to maritime shipping to medical instruments. The formation of proteic films can adversely affect the performance of materials and is often a limiting factor in device effectiveness. In many instances such as sensors or medical implants, regular cleaning or disposal of the instrument is not a viable option, thus there exists a demand for additional means to prevent nonspecific protein adsorption. Existing protein resistant coating options are still not completely effective, and monolayer protected metal nanoparticle coatings could be a superior means by which to prevent protein adsorption onto material surfaces.

Department dc:contributor.department

Massachusetts Institute of Technology. Department of Materials Science and Engineering

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2005

Author dc:creator

• Wu, Diana J

Advisor dc:contributor.advisor

• Francesco Stellacci.

• Materials Science and Engineering.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/33617

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/33617