{"id":{"repo_id":"mit","oai_identifier":"oai:dspace.mit.edu:1721.1/33617"},"canonical_url":"https://search.dev.ndltd.org/etd/mit/oai:dspace.mit.edu:1721.1/33617","repository":{"repo_id":"mit","name":"MIT","base_url":"https://dspace.mit.edu/oai/request"},"display":{"title":"Evaluation of monolayer protected metal nanoparticle technology","abstract":"Self assembling nanostructured nanoparticles represent a new class of synthesized materials with unique functionality. Such monolayer protected metal nanoparticles are capable of resisting protein adsorption, and if utilized as a coating could have broad application in a wide range of industries from consumer products to maritime shipping to medical instruments. The formation of proteic films can adversely affect the performance of materials and is often a limiting factor in device effectiveness. In many instances such as sensors or medical implants, regular cleaning or disposal of the instrument is not a viable option, thus there exists a demand for additional means to prevent nonspecific protein adsorption. Existing protein resistant coating options are still not completely effective, and monolayer protected metal nanoparticle coatings could be a superior means by which to prevent protein adsorption onto material surfaces.","abstract_html":"Self assembling nanostructured nanoparticles represent a new class of synthesized materials with unique functionality. Such monolayer protected metal nanoparticles are capable of resisting protein adsorption, and if utilized as a coating could have broad application in a wide range of industries from consumer products to maritime shipping to medical instruments. The formation of proteic films can adversely affect the performance of materials and is often a limiting factor in device effectiveness. In many instances such as sensors or medical implants, regular cleaning or disposal of the instrument is not a viable option, thus there exists a demand for additional means to prevent nonspecific protein adsorption. Existing protein resistant coating options are still not completely effective, and monolayer protected metal nanoparticle coatings could be a superior means by which to prevent protein adsorption onto material surfaces.","abstract_has_math":false,"creators":["Wu, Diana J"],"institution":"Massachusetts Institute of Technology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":"Massachusetts Institute of Technology. Department of Materials Science and Engineering","school":null,"contributors":[],"advisors":["Francesco Stellacci."],"committee_chairs":[],"committee_members":[],"year":2005,"date_issued":"2005","date_published":"2005","updated_at":"2026-07-22T22:20:50Z","subjects":["Materials Science and Engineering."],"languages":["eng"],"rights":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission."],"rights_urls":["http://dspace.mit.edu/handle/1721.1/7582"],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/1721.1/33617","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Francesco Stellacci."]},{"key":"dc:contributor.department","label":"Department","values":["Massachusetts Institute of Technology. Department of Materials Science and Engineering"]},{"key":"dc:contributor.other","label":"Dc Contributor Other","values":["Massachusetts Institute of Technology. Dept. of Materials Science and Engineering."]},{"key":"dc:creator","label":"Author","values":["Wu, Diana J"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2006-07-31T15:17:28Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2006-07-31T15:17:28Z"]},{"key":"dc:date.issued","label":"Date","values":["2005"]},{"key":"dc:publisher","label":"Institution","values":["Massachusetts Institute of Technology"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Materials Science and Engineering."]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]},{"key":"dc:rights","label":"Dc Rights","values":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission."]},{"key":"dc:rights.uri","label":"Rights URI","values":["http://dspace.mit.edu/handle/1721.1/7582"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/1721.1/33617"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2005.","Includes bibliographical references (p. 73-77)."]},{"key":"dc:description.abstract","label":"Abstract","values":["Self assembling nanostructured nanoparticles represent a new class of synthesized materials with unique functionality. Such monolayer protected metal nanoparticles are capable of resisting protein adsorption, and if utilized as a coating could have broad application in a wide range of industries from consumer products to maritime shipping to medical instruments. The formation of proteic films can adversely affect the performance of materials and is often a limiting factor in device effectiveness. In many instances such as sensors or medical implants, regular cleaning or disposal of the instrument is not a viable option, thus there exists a demand for additional means to prevent nonspecific protein adsorption. Existing protein resistant coating options are still not completely effective, and monolayer protected metal nanoparticle coatings could be a superior means by which to prevent protein adsorption onto material surfaces.","(cont.) This paper explores the commercialization potential of monolayer protected metal nanoparticle coatings for protein resistance; identifying application potential, evaluating potential markets, exploring intellectual property, analyzing the economics of monolayer protected metal nanoparticle synthesis, examining existing technologies, and assessing in depth the medical device industry and entry into the US cardiovascular device market."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["M.Eng."]},{"key":"dc:format.mimetype","label":"Dc Format Mimetype","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Evaluation of monolayer protected metal nanoparticle technology"]}]}],"canonical_facts":{"dc:contributor.advisor":["Francesco Stellacci."],"dc:contributor.department":["Massachusetts Institute of Technology. Department of Materials Science and Engineering"],"dc:contributor.other":["Massachusetts Institute of Technology. Dept. of Materials Science and Engineering."],"dc:creator":["Wu, Diana J"],"dc:date.accessioned":["2006-07-31T15:17:28Z"],"dc:date.available":["2006-07-31T15:17:28Z"],"dc:date.issued":["2005"],"dc:description":["Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2005.","Includes bibliographical references (p. 73-77)."],"dc:description.abstract":["Self assembling nanostructured nanoparticles represent a new class of synthesized materials with unique functionality. Such monolayer protected metal nanoparticles are capable of resisting protein adsorption, and if utilized as a coating could have broad application in a wide range of industries from consumer products to maritime shipping to medical instruments. The formation of proteic films can adversely affect the performance of materials and is often a limiting factor in device effectiveness. In many instances such as sensors or medical implants, regular cleaning or disposal of the instrument is not a viable option, thus there exists a demand for additional means to prevent nonspecific protein adsorption. Existing protein resistant coating options are still not completely effective, and monolayer protected metal nanoparticle coatings could be a superior means by which to prevent protein adsorption onto material surfaces.","(cont.) This paper explores the commercialization potential of monolayer protected metal nanoparticle coatings for protein resistance; identifying application potential, evaluating potential markets, exploring intellectual property, analyzing the economics of monolayer protected metal nanoparticle synthesis, examining existing technologies, and assessing in depth the medical device industry and entry into the US cardiovascular device market."],"dc:description.degree":["M.Eng."],"dc:format.mimetype":["application/pdf"],"dc:identifier.uri":["http://hdl.handle.net/1721.1/33617"],"dc:language.iso":["eng"],"dc:publisher":["Massachusetts Institute of Technology"],"dc:rights":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission."],"dc:rights.uri":["http://dspace.mit.edu/handle/1721.1/7582"],"dc:subject":["Materials Science and Engineering."],"dc:title":["Evaluation of monolayer protected metal nanoparticle technology"],"dc:type":["Thesis"]},"updated_at":"2026-07-22T22:20:50Z"}