Instrumentation to characterize needle insertion into biological tissue

The Transdermal Drug Delivery Project in the BioInstrumentation Laboratory involves the design of a device to deliver drugs through the human skin using micro needles. It is crucial to characterize the insertion of micro needles into biological tissues. Hence, instrumentation will be designed and fabricated for the characterization of micro needle insertion. This thesis focuses on the design and fabrication of such instrumentation. The instrument is multi-modal, multi-axis, mobile and compact. It is capable of precise insertion positioning and acquiring accurate insertion force data. Characterization of micro needle insertion into biological tissues is done successfully using the data acquired by this instrument and an existing physical force model.

Department dc:contributor.department

Massachusetts Institute of Technology. Dept. of Mechanical Engineering.

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2002

Author dc:creator

• Chan, Wilson (Wilson Sian Chew), 1976-

Advisor dc:contributor.advisor

• Ian W. Hunter.

• Mechanical Engineering.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/17541

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/17541