{"id":{"repo_id":"mit","oai_identifier":"oai:dspace.mit.edu:1721.1/17541"},"canonical_url":"https://search.dev.ndltd.org/etd/mit/oai:dspace.mit.edu:1721.1/17541","repository":{"repo_id":"mit","name":"MIT","base_url":"https://dspace.mit.edu/oai/request"},"display":{"title":"Instrumentation to characterize needle insertion into biological tissue","abstract":"The Transdermal Drug Delivery Project in the BioInstrumentation Laboratory involves the design of a device to deliver drugs through the human skin using micro needles. It is crucial to characterize the insertion of micro needles into biological tissues. Hence, instrumentation will be designed and fabricated for the characterization of micro needle insertion. This thesis focuses on the design and fabrication of such instrumentation. The instrument is multi-modal, multi-axis, mobile and compact. It is capable of precise insertion positioning and acquiring accurate insertion force data. Characterization of micro needle insertion into biological tissues is done successfully using the data acquired by this instrument and an existing physical force model.","abstract_html":"The Transdermal Drug Delivery Project in the BioInstrumentation Laboratory involves the design of a device to deliver drugs through the human skin using micro needles. It is crucial to characterize the insertion of micro needles into biological tissues. Hence, instrumentation will be designed and fabricated for the characterization of micro needle insertion. This thesis focuses on the design and fabrication of such instrumentation. The instrument is multi-modal, multi-axis, mobile and compact. It is capable of precise insertion positioning and acquiring accurate insertion force data. Characterization of micro needle insertion into biological tissues is done successfully using the data acquired by this instrument and an existing physical force model.","abstract_has_math":false,"creators":["Chan, Wilson (Wilson Sian Chew), 1976-"],"institution":"Massachusetts Institute of Technology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":"Massachusetts Institute of Technology. Dept. of Mechanical Engineering.","school":null,"contributors":[],"advisors":["Ian W. Hunter."],"committee_chairs":[],"committee_members":[],"year":2002,"date_issued":"2002","date_published":"2002","updated_at":"2026-07-22T22:22:13Z","subjects":["Mechanical Engineering."],"languages":["eng"],"rights":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission."],"rights_urls":["http://dspace.mit.edu/handle/1721.1/7582"],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/1721.1/17541","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Ian W. Hunter."]},{"key":"dc:contributor.department","label":"Department","values":["Massachusetts Institute of Technology. Dept. of Mechanical Engineering."]},{"key":"dc:contributor.other","label":"Dc Contributor Other","values":["Massachusetts Institute of Technology. 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It is crucial to characterize the insertion of micro needles into biological tissues. Hence, instrumentation will be designed and fabricated for the characterization of micro needle insertion. This thesis focuses on the design and fabrication of such instrumentation. The instrument is multi-modal, multi-axis, mobile and compact. It is capable of precise insertion positioning and acquiring accurate insertion force data. Characterization of micro needle insertion into biological tissues is done successfully using the data acquired by this instrument and an existing physical force model."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["S.M."]},{"key":"dc:format.mimetype","label":"Dc Format Mimetype","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Instrumentation to characterize needle insertion into biological tissue"]}]}],"canonical_facts":{"dc:contributor.advisor":["Ian W. Hunter."],"dc:contributor.department":["Massachusetts Institute of Technology. Dept. of Mechanical Engineering."],"dc:contributor.other":["Massachusetts Institute of Technology. Dept. of Mechanical Engineering."],"dc:creator":["Chan, Wilson (Wilson Sian Chew), 1976-"],"dc:date.accessioned":["2005-06-02T16:06:35Z"],"dc:date.available":["2005-06-02T16:06:35Z"],"dc:date.issued":["2002"],"dc:description":["Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2002.","Includes bibliographical references (leaves 52-53)."],"dc:description.abstract":["The Transdermal Drug Delivery Project in the BioInstrumentation Laboratory involves the design of a device to deliver drugs through the human skin using micro needles. It is crucial to characterize the insertion of micro needles into biological tissues. Hence, instrumentation will be designed and fabricated for the characterization of micro needle insertion. This thesis focuses on the design and fabrication of such instrumentation. The instrument is multi-modal, multi-axis, mobile and compact. It is capable of precise insertion positioning and acquiring accurate insertion force data. Characterization of micro needle insertion into biological tissues is done successfully using the data acquired by this instrument and an existing physical force model."],"dc:description.degree":["S.M."],"dc:format.mimetype":["application/pdf"],"dc:identifier.uri":["http://hdl.handle.net/1721.1/17541"],"dc:language.iso":["eng"],"dc:publisher":["Massachusetts Institute of Technology"],"dc:rights":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission."],"dc:rights.uri":["http://dspace.mit.edu/handle/1721.1/7582"],"dc:subject":["Mechanical Engineering."],"dc:title":["Instrumentation to characterize needle insertion into biological tissue"],"dc:type":["Thesis"]},"updated_at":"2026-07-22T22:22:13Z"}