If you build it, they will run : the role of clinical trial infrastructure in neglected disease R&D

I investigate the role of country level clinical trial infrastructure on research and development (R&D) levels for neglected tropical diseases concentrated in those countries. Pre-existing clinical trial infrastructure in a location can affect the cost and time of clinical trials carried out there, thus influence returns on investments for diseases that are located in different places. Using a newly constructed dataset I assess the components that make up a country's clinical trial infrastructure, which varies for countries in different stages of development. Using data on neglected tropical disease global disease burdens and research levels, I find that the level of R&D into diseases concentrated in countries with poorer clinical trial infrastructure is lower than that for diseases concentrated in countries with better infrastructure. This paper suggests a need for further work into the role of research infrastructure in developing countries and its role on innovation outcomes for issues affecting the world's poorest countries.

Department dc:contributor.department

Sloan School of Management.

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2018

Author dc:creator

• Fry, Caroline Viola

Advisor dc:contributor.advisor

• Pierre Azoulay.

• Sloan School of Management.

Statement dc:rights

• MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/118009

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/118009