{"id":{"repo_id":"mit","oai_identifier":"oai:dspace.mit.edu:1721.1/118009"},"canonical_url":"https://search.dev.ndltd.org/etd/mit/oai:dspace.mit.edu:1721.1/118009","repository":{"repo_id":"mit","name":"MIT","base_url":"https://dspace.mit.edu/oai/request"},"display":{"title":"If you build it, they will run : the role of clinical trial infrastructure in neglected disease R&D","abstract":"I investigate the role of country level clinical trial infrastructure on research and development (R&D) levels for neglected tropical diseases concentrated in those countries. Pre-existing clinical trial infrastructure in a location can affect the cost and time of clinical trials carried out there, thus influence returns on investments for diseases that are located in different places. Using a newly constructed dataset I assess the components that make up a country's clinical trial infrastructure, which varies for countries in different stages of development. Using data on neglected tropical disease global disease burdens and research levels, I find that the level of R&D into diseases concentrated in countries with poorer clinical trial infrastructure is lower than that for diseases concentrated in countries with better infrastructure. This paper suggests a need for further work into the role of research infrastructure in developing countries and its role on innovation outcomes for issues affecting the world's poorest countries.","abstract_html":"I investigate the role of country level clinical trial infrastructure on research and development (R&D) levels for neglected tropical diseases concentrated in those countries. Pre-existing clinical trial infrastructure in a location can affect the cost and time of clinical trials carried out there, thus influence returns on investments for diseases that are located in different places. Using a newly constructed dataset I assess the components that make up a country's clinical trial infrastructure, which varies for countries in different stages of development. Using data on neglected tropical disease global disease burdens and research levels, I find that the level of R&D into diseases concentrated in countries with poorer clinical trial infrastructure is lower than that for diseases concentrated in countries with better infrastructure. This paper suggests a need for further work into the role of research infrastructure in developing countries and its role on innovation outcomes for issues affecting the world's poorest countries.","abstract_has_math":false,"creators":["Fry, Caroline Viola"],"institution":"Massachusetts Institute of Technology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":"Sloan School of Management.","school":null,"contributors":[],"advisors":["Pierre Azoulay."],"committee_chairs":[],"committee_members":[],"year":2018,"date_issued":"2018","date_published":"2018","updated_at":"2026-07-22T22:21:44Z","subjects":["Sloan School of Management."],"languages":["eng"],"rights":["MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission."],"rights_urls":["http://dspace.mit.edu/handle/1721.1/7582"],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/1721.1/118009","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Pierre Azoulay."]},{"key":"dc:contributor.department","label":"Department","values":["Sloan School of Management."]},{"key":"dc:contributor.other","label":"Dc Contributor Other","values":["Sloan School of Management."]},{"key":"dc:creator","label":"Author","values":["Fry, Caroline Viola"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2018-09-17T15:53:39Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2018-09-17T15:53:39Z"]},{"key":"dc:date.issued","label":"Date","values":["2018"]},{"key":"dc:publisher","label":"Institution","values":["Massachusetts Institute of Technology"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Sloan School of Management."]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]},{"key":"dc:rights","label":"Dc Rights","values":["MIT theses are protected by copyright. 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Pre-existing clinical trial infrastructure in a location can affect the cost and time of clinical trials carried out there, thus influence returns on investments for diseases that are located in different places. Using a newly constructed dataset I assess the components that make up a country's clinical trial infrastructure, which varies for countries in different stages of development. Using data on neglected tropical disease global disease burdens and research levels, I find that the level of R&D into diseases concentrated in countries with poorer clinical trial infrastructure is lower than that for diseases concentrated in countries with better infrastructure. This paper suggests a need for further work into the role of research infrastructure in developing countries and its role on innovation outcomes for issues affecting the world's poorest countries."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["S.M. in Management Research"]},{"key":"dc:title","label":"Title","values":["If you build it, they will run : the role of clinical trial infrastructure in neglected disease R&D"]}]}],"canonical_facts":{"dc:contributor.advisor":["Pierre Azoulay."],"dc:contributor.department":["Sloan School of Management."],"dc:contributor.other":["Sloan School of Management."],"dc:creator":["Fry, Caroline Viola"],"dc:date.accessioned":["2018-09-17T15:53:39Z"],"dc:date.available":["2018-09-17T15:53:39Z"],"dc:date.issued":["2018"],"dc:description":["Thesis: S.M. in Management Research, Massachusetts Institute of Technology, Sloan School of Management, 2018.","Cataloged from PDF version of thesis.","Includes bibliographical references (pages 21-22)."],"dc:description.abstract":["I investigate the role of country level clinical trial infrastructure on research and development (R&D) levels for neglected tropical diseases concentrated in those countries. Pre-existing clinical trial infrastructure in a location can affect the cost and time of clinical trials carried out there, thus influence returns on investments for diseases that are located in different places. Using a newly constructed dataset I assess the components that make up a country's clinical trial infrastructure, which varies for countries in different stages of development. Using data on neglected tropical disease global disease burdens and research levels, I find that the level of R&D into diseases concentrated in countries with poorer clinical trial infrastructure is lower than that for diseases concentrated in countries with better infrastructure. This paper suggests a need for further work into the role of research infrastructure in developing countries and its role on innovation outcomes for issues affecting the world's poorest countries."],"dc:description.degree":["S.M. in Management Research"],"dc:identifier.uri":["http://hdl.handle.net/1721.1/118009"],"dc:language.iso":["eng"],"dc:publisher":["Massachusetts Institute of Technology"],"dc:rights":["MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission."],"dc:rights.uri":["http://dspace.mit.edu/handle/1721.1/7582"],"dc:subject":["Sloan School of Management."],"dc:title":["If you build it, they will run : the role of clinical trial infrastructure in neglected disease R&D"],"dc:type":["Thesis"]},"updated_at":"2026-07-22T22:21:44Z"}