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University of Mississippi

Progress Toward the Synthesis of 3-Methoxyflavones as Potential Antioxidants, Neuroprotective Agents, and Trifluoromethylated 19F NMR Probes

Abstract

dc:description.abstract

The total synthesis of polyhydroxylated flavones have proven to be challenging, due to the presence of more than one hydroxyl group. Direct cyclization was not successful in any of the attempts. However, by using a silyl protecting group, the cyclization was feasible. Other reactions like the Friedel-Crafts acylation and selective protection of phenols were also difficult.

Degree

thesis:*
Name thesis:degree_name
M.S. in Pharmaceutical Science
Level thesis:degree_level
Thesis
Discipline thesis:degree_discipline
Pharmaceutics and Drug Delivery
Year dc:date.available
2019

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Alkhodier, Reem
Contributors dc:contributor
  • David A. Colby
  • David Colby
  • Jared H. Delcamp

Subjects

dc:subject × 3

Identifiers

dc:identifier.*
Repository record dc:identifier
https://egrove.olemiss.edu/etd/1574
OAI identifier oai:identifier
oai:egrove.olemiss.edu:etd-2573

Chain of custody

source
Harvested from
University of Mississippi
Base URL
egrove.olemiss.edu/do/oai/
Last updated
2026-07-24
Source record
OAI-PMH GetRecord
citation

Alkhodier, Reem. Progress Toward the Synthesis of 3-Methoxyflavones as Potential Antioxidants, Neuroprotective Agents, and Trifluoromethylated 19F NMR Probes. Thesis thesis, 2019. https://egrove.olemiss.edu/etd/1574