Efficacy of Cognitive Therapy and Pharmacotherapy In Depression: A Meta-Analysis

<p>A meta-analysis comparing the long-term effectiveness of cognitive behavioral therapy (CBT) and pharmacotherapy in preventing relapse following treatment discontinuation was performed using published studies of depressed participants. Twenty-three articles met inclusionary criteria and were included in the analyses. Weighted effect sizes and moderators, treatment type, were calculated using statistical analysis software. Initially, fixed effects models were applied to the data, but due to significant between-group heterogeneity that could not be fully explained by treatment type, mixed effect models were used to account for the residual heterogeneity. Results indicated that overall, depressed individuals treated to remission with CBT evidence decreased relapse rates up to 104 weeks post-treatment compared to those treated with pharmacotherapy. This finding was specifically supported at 52 weeks follow-up. However, while this finding was not significant at 104 weeks, the clear trend was in support of CBT. These findings have important implications for the effective long-term management of the recurrent nature of major depression.</p>

Name thesis:degree_name

Doctor of Psychology (PsyD)

Level thesis:degree_level

Doctoral Project

Discipline thesis:degree_discipline

Psychology

Year

2007

Author dc:creator

• Michel, Daniel B.

Contributors dc:contributor

• Kendal C. Boyd
• Louis E. Jenkins
• David A. Vermeersch

• Biostatistics
• Cognitive Behavioral Therapy
• Pharmacy and Pharmaceutical Sciences
• Psychology
• Depression; Depressive Disorder -- therapy; Cognitive Therapy; Drug Therapy.

Statement dc:rights

• This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Language dc:language

English

Repository record dc:identifier

https://scholarsrepository.llu.edu/etd/1596

OAI identifier oai:identifier

oai:scholarsrepository.llu.edu:etd-2347