The application of microneedles fabricated by diffraction ultraviolet (uv) lithography

This report summarizes a series of research results based on UV-light microneedles manufacturing technology. The content can be divided into three parts: Discussing the effect of wavelength on UV lithography microneedle fabrication results, a fabrication process of a wound patch that includes an array of light-focusing microneedle and self-actuatable and light-filtering hydrogel, and fabrication of hollow microneedle and hollow-well microneedle. UV diffraction lithography has been introduced as a rapid and batch-friendly microneedle fabrication method. The shape and aspect ratio can be defined by masks with variable patterns. The shape of the UV light source is changed through the mask, and different patterns are mapped on the photosensitive material layer so as to make various 3d structures. In this manufacturing process, we found that the wavelength of the light source can affect the experimental results. Therefore, the research began by testing the relationship between wavelength and the shape of microneedles fabricated by UV lithography. After that, I joined the MAP (Microneedle-array patch) project. In this project, all the microneedles we used were fabricated by UV lithography. As mentioned above, the MAP project is trying to develop a wound-healing microneedle array that loads 9 solid microneedles. Solid microneedles are only one type of microneedle. In order to increase the functionality of the microneedles array, we also Explore the method of fabricating hollow-well microneedles.

Grantor dc:publisher

Kansas State University

Year dc:date.issued

2023

Author dc:creator

• Li, Yuankai

• Microneedle

Statement dc:rights

• © the author. This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).

Licence dc:rights.uri

• http://rightsstatements.org/vocab/InC/1.0/

Language dc:language.iso

en_US

Handle dc:identifier.uri

https://hdl.handle.net/2097/43328

OAI record oai:identifier

https://krex.k-state.edu/server/oai/request?verb=GetRecord&metadataPrefix=dim&identifier=oai%3Akrex.k-state.edu%3A2097%2F43328