Exploring the biofilm of Candida auris as it relates to persistence in clinical setting and susceptibility to antimicrobials

<p>The rapid rise of drug-resistant pathogens is a global health concern. Known pathogens are acquiring resistance to many commonly used drugs, while new drug-resistant pathogens are emerging. These resistant pathogens are responsible for many healthcare-associated infections (HAI) [1, 2]. <em>Candida auris</em> is among these emerging drug-resistant pathogens, first described in 2009. The CDC labels <em>C. auris</em> at the highest level of global public health threat [3,4]. Effective methods of decolonization and control of the organisms have yet to be established, as it is resistant to many agents used for microbial control. Recent research has found that <em>C. auris </em>has the capacity to form biofilms on healthcare surfaces and human skin [1,2]. This research aims to evaluate the role of biofilm formation of <em>C. auris</em> in its heightened antimicrobial resistance and high transmissibility, causing outbreaks in clinical settings. This study will explore the biofilm formation of <em>C. auris</em>, focusing on structural characteristics, nutrient utilization, and antimicrobial resistance. <strong></strong></p>

Name thesis:degree_name

Master of Science in Integrative Biology (MSIB)

Level thesis:degree_level

Thesis

Discipline thesis:degree_discipline

Biology

Year dc:date.available

2021

Author dc:creator

• Butts, bethany

Contributors dc:contributor

• Dr. Martin Hudson
• Dr. Melanie Griffin
• Dr. Scott Nowak

• Candida auris
• Biofilms
• Antimicrobial Susceptibility
• fungal pathogen
• Biology
• Integrative Biology

Repository record dc:identifier

https://digitalcommons.kennesaw.edu/integrbiol_etd/71

OAI identifier oai:identifier

oai:digitalcommons.kennesaw.edu:integrbiol_etd-1071