Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Candida auris"”.
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Candida auris stressztűrési jellemzőinek vizsgálata
… epidemiológiai adatai alapján, kétségkívül a Candida auris tekinthető az egyik legnagyobb globális fenyegetésnek, mely elsősorban az antimikotikum rezisztenciájával és az általa okozott infekciók magas mortalitási arányával magyarázható. Továbbá, magas stressztűrő képesség jellemzi, melynek …
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A tractable nematode model for the emerging fungal pathogen, Candida auris
<p><em>Candida auris</em> is an emerging multidrug-resistant opportunistic fungal pathogen. It</p> <p>poses a significant threat to immunocompromised patients and those with prolonged stays in</p> <p>healthcare facilities. <em>C. auris</em> spreads rapidly in health care facilities through …
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The evolution of virulence in Candida auris determined through experimental, ecological and epidemiological approaches
Candida auris is an emerging human fungal pathogen that has rapidly transitioned from its first description in a case of ear infection in Japan in 2008 to a global public health threat featuring the spread of six clades across six continents. Major problems concerning its management include: (i) …
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Discovery and development of novel antifungal agents for the treatment of Candida auris infections
… pathogens responsible for these infections are Candida, Cryptococcus, and Aspergillus. Currently, treatment options for invasive fungal infections are limited to three main classes of antifungal drugs: azoles, polyenes, and echinocandins. The emergence of new fungal species, such as Candida …
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Substrate Utilization of the Emerging Fungal Pathogen, Candida auris, and the Antifungal Activity of Select Essential Oils
<p><em>Candida auris </em>is an emerging fungal pathogen that commonly causes nosocomial blood infections in the immunocompromised. Three factors make this emerging pathogen a global threat. First, it is frequently misidentified by commonly used diagnostic platforms. Second, it is able to survive …
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Exploring the biofilm of Candida auris as it relates to persistence in clinical setting and susceptibility to antimicrobials
… infections (HAI) [1, 2]. <em>Candida auris</em> is among these emerging drug-resistant pathogens, first described in 2009. The CDC labels <em>C. auris</em> at the highest level of global public health threat [3,4]. Effective methods of decolonization and control of the …
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Characterisation and Screening of secondary metabolites from Commiphora viminea (Burtt Davy, Burseraceae) Engl. for antifungal properties against Candida auris
… and diluted serially across the plate against Candida auris, Candida albicans, Candida glabrata, Candida parapsilosis, and Candida tropicalis multidrug-resistant fungal pathogens. The results revealed moderate inhibitory activity, particularly in the acetone and ethyl acetate extracts of the …
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Molecular Analysis of Phenotypic Diversity in Human Fungal Pathogens
… conditions experienced in a mammalian host. Candida species can colonize various niches in the human body making them common commensals of the mucosal microbiota, where the maintenance of a stable host-fungus relationship is presumably critical for avoiding disease. However, the importance of …
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Exploiting Chemical Libraries to Identify and Characterize Novel Bioactives with Efficacy Against Pathogenic Candida Species
Candida species are amongst the most prevalent causes of systemic fungal infections, which account for over 1.5 million annual fatalities. Candida albicans represents the most common etiological agent; however, the rate of infections caused by non-albicans Candida species continues to rise. Here, I …
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Plataforma de monitoreo y pronóstico de impacto de enfermedades infecciosas en la sociedad
… humana, el virus del papiloma humano y el hongo Candida auris. Con relaci on al primer objetivo, se logr o desarrollar un m odulo capaz de recolectar informaci on de estas enfermedades. Adem as, se cre o una base de datos para alojar la informaci on recuperada desde estas fuentes, con un total de …
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Developing novel drug combinations for treatment of invasive fungal infections
… majority of invasive fungal infections include Candida, Cryptococcus, and Aspergillus. The current treatment options for invasive fungal infections are restricted to three classes of antifungals: Azoles, polyenes, and echinocandins. The emergence of new fungal species, especially C. auris, …