The Impact of Long Term Opioid Medication on Oral Antihyperglycmic Medication Adherence and Subsequent Type 2 Diabetes Mellitus Related Hospitalization Risk among Individuals with Type 2 Diabetes Mellitus: A Retrospective Database Analysis

Prescription opioids are a highly prescribed class of medication, which when administered over long durations can lead to negative effects (e.g., addiction, non-medical use). Prescription opioids are often prescribed concomitantly with antihyperglycemic medication among patients with T2DM. Due to known associated negative effects of prescription opioids, it is imperative to study the impact of long term opioid use of antihyperglycemic medication when prescribed concomitantly. Therefore, the primary aim of this study was to examine if there is any effect of long-term opioid use on antihyperglycemic medication adherence when the two medication classes are prescribed concomitantly among patients with T2DM. Additionally, this study also examined whether the duration of opioid use and antihyperglycemic adherence has any potential impact on subsequent diabetes related hospitalizations.

Name thesis:degree_name

Doctor of Philosophy

Level thesis:degree_level

Doctoral

Discipline thesis:degree_discipline

Health Outcomes and Policy

Grantor

University of Houston

Year dc:date.issued

2016

Author dc:creator

• Atreja, Nipun

Advisor dc:contributor.advisor

• Fleming, Marc L.

Committee members dc:contributor.committeemember

• Chen, Hua
• Johnson, Michael L.
• Zhivan, Natalia
• Todd, Knox H.

• T2DM
• Antihyperglycemics
• Prescription opioids

Statement dc:rights

• The author of this work is the copyright owner. UH Libraries and the Texas Digital Library have their permission to store and provide access to this work. Further transmission, reproduction, or presentation of this work is prohibited except with permission of the author(s).

Language dc:language.iso

eng

Handle dc:identifier.uri

https://hdl.handle.net/10657/5438

OAI identifier oai:identifier

oai:uh-ir.tdl.org:10657/5438