{"id":{"repo_id":"houston","oai_identifier":"oai:uh-ir.tdl.org:10657/5438"},"canonical_url":"https://search.dev.ndltd.org/etd/houston/oai:uh-ir.tdl.org:10657/5438","repository":{"repo_id":"houston","name":"University of Houston","base_url":"https://uh-ir.tdl.org/server/oai/request"},"display":{"title":"The Impact of Long Term Opioid Medication on Oral Antihyperglycmic Medication Adherence and Subsequent Type 2 Diabetes Mellitus Related Hospitalization Risk among Individuals with Type 2 Diabetes Mellitus: A Retrospective Database Analysis","abstract":"Prescription opioids are a highly prescribed class of medication, which when administered over long durations can lead to negative effects (e.g., addiction, non-medical use). Prescription opioids are often prescribed concomitantly with antihyperglycemic medication among patients with T2DM. Due to known associated negative effects of prescription opioids, it is imperative to study the impact of long term opioid use of antihyperglycemic medication when prescribed concomitantly. Therefore, the primary aim of this study was to examine if there is any effect of long-term opioid use on antihyperglycemic medication adherence when the two medication classes are prescribed concomitantly among patients with T2DM. Additionally, this study also examined whether the duration of opioid use and antihyperglycemic adherence has any potential impact on subsequent diabetes related hospitalizations.","abstract_html":"Prescription opioids are a highly prescribed class of medication, which when administered over long durations can lead to negative effects (e.g., addiction, non-medical use). Prescription opioids are often prescribed concomitantly with antihyperglycemic medication among patients with T2DM. Due to known associated negative effects of prescription opioids, it is imperative to study the impact of long term opioid use of antihyperglycemic medication when prescribed concomitantly. Therefore, the primary aim of this study was to examine if there is any effect of long-term opioid use on antihyperglycemic medication adherence when the two medication classes are prescribed concomitantly among patients with T2DM. Additionally, this study also examined whether the duration of opioid use and antihyperglycemic adherence has any potential impact on subsequent diabetes related hospitalizations.","abstract_has_math":false,"creators":["Atreja, Nipun"],"institution":"University of Houston","degree_name":"Doctor of Philosophy","degree_level":"Doctoral","degree_discipline":"Health Outcomes and Policy","degree_department":null,"school":null,"contributors":[],"advisors":["Fleming, Marc L."],"committee_chairs":[],"committee_members":["Chen, Hua","Johnson, Michael L.","Zhivan, Natalia","Todd, Knox H."],"year":2016,"date_issued":"2016-12","date_published":"2016-12","updated_at":"2026-07-24T02:32:34Z","subjects":["T2DM","Antihyperglycemics","Prescription opioids"],"languages":["eng"],"rights":["The author of this work is the copyright owner. UH Libraries and the Texas Digital Library have their permission to store and provide access to this work. Further transmission, reproduction, or presentation of this work is prohibited except with permission of the author(s)."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://hdl.handle.net/10657/5438","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Fleming, Marc L."]},{"key":"dc:contributor.committeemember","label":"Committee Member","values":["Chen, Hua","Johnson, Michael L.","Zhivan, Natalia","Todd, Knox H."]},{"key":"dc:creator","label":"Author","values":["Atreja, Nipun"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2019-11-17T21:23:45Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2019-11-17T21:23:45Z"]},{"key":"dc:date.issued","label":"Date","values":["2016-12"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Health Outcomes and Policy"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Doctoral"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Doctor of Philosophy"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Houston"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["T2DM","Antihyperglycemics","Prescription opioids"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]},{"key":"dc:rights","label":"Dc Rights","values":["The author of this work is the copyright owner. UH Libraries and the Texas Digital Library have their permission to store and provide access to this work. Further transmission, reproduction, or presentation of this work is prohibited except with permission of the author(s)."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://hdl.handle.net/10657/5438"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Prescription opioids are a highly prescribed class of medication, which when administered over long durations can lead to negative effects (e.g., addiction, non-medical use). Prescription opioids are often prescribed concomitantly with antihyperglycemic medication among patients with T2DM. Due to known associated negative effects of prescription opioids, it is imperative to study the impact of long term opioid use of antihyperglycemic medication when prescribed concomitantly. Therefore, the primary aim of this study was to examine if there is any effect of long-term opioid use on antihyperglycemic medication adherence when the two medication classes are prescribed concomitantly among patients with T2DM. Additionally, this study also examined whether the duration of opioid use and antihyperglycemic adherence has any potential impact on subsequent diabetes related hospitalizations."]},{"key":"dc:format.mimetype","label":"Dc Format Mimetype","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["The Impact of Long Term Opioid Medication on Oral Antihyperglycmic Medication Adherence and Subsequent Type 2 Diabetes Mellitus Related Hospitalization Risk among Individuals with Type 2 Diabetes Mellitus: A Retrospective Database Analysis"]}]}],"canonical_facts":{"dc:contributor.advisor":["Fleming, Marc L."],"dc:contributor.committeemember":["Chen, Hua","Johnson, Michael L.","Zhivan, Natalia","Todd, Knox H."],"dc:creator":["Atreja, Nipun"],"dc:date.accessioned":["2019-11-17T21:23:45Z"],"dc:date.available":["2019-11-17T21:23:45Z"],"dc:date.issued":["2016-12"],"dc:description.abstract":["Prescription opioids are a highly prescribed class of medication, which when administered over long durations can lead to negative effects (e.g., addiction, non-medical use). Prescription opioids are often prescribed concomitantly with antihyperglycemic medication among patients with T2DM. Due to known associated negative effects of prescription opioids, it is imperative to study the impact of long term opioid use of antihyperglycemic medication when prescribed concomitantly. Therefore, the primary aim of this study was to examine if there is any effect of long-term opioid use on antihyperglycemic medication adherence when the two medication classes are prescribed concomitantly among patients with T2DM. Additionally, this study also examined whether the duration of opioid use and antihyperglycemic adherence has any potential impact on subsequent diabetes related hospitalizations."],"dc:format.mimetype":["application/pdf"],"dc:identifier.uri":["https://hdl.handle.net/10657/5438"],"dc:language.iso":["eng"],"dc:rights":["The author of this work is the copyright owner. UH Libraries and the Texas Digital Library have their permission to store and provide access to this work. Further transmission, reproduction, or presentation of this work is prohibited except with permission of the author(s)."],"dc:subject":["T2DM","Antihyperglycemics","Prescription opioids"],"dc:title":["The Impact of Long Term Opioid Medication on Oral Antihyperglycmic Medication Adherence and Subsequent Type 2 Diabetes Mellitus Related Hospitalization Risk among Individuals with Type 2 Diabetes Mellitus: A Retrospective Database Analysis"],"thesis:degree_discipline":["Health Outcomes and Policy"],"thesis:degree_level":["Doctoral"],"thesis:degree_name":["Doctor of Philosophy"],"thesis:institution_name":["University of Houston"]},"updated_at":"2026-07-24T02:32:34Z"}