ΣΥΜΒΟΛΗ ΣΤΗ ΜΕΛΕΤΗ ΤΟΥ ΡΟΛΟΥ ΤΩΝ ΟΙΣΤΡΟΓΟΝΩΝ ΣΤΗΝ ΟΣΤΙΚΗ ΕΠΟΥΛΩΣΗ (ΚΑΤΑΓΜΑ ΚΑΤΩ ΓΝΑΘΟΥ). (ΠΕΙΡΑΜΑΤΙΚΗ ΜΕΛΕΤΗ)

THE STIMULUS FOR THE STUDY OF ESTROGENS' INFLUENCE ON THE HEALING PROCESS OF FRACTURES WAS THEIR KNOWN CONTRIBUTION TO THE RESTRAINT OF THE OSTEOLYTIC PROCESSWHICH OCCURS IN OSTEOPOROSIS. FRACTURES WERE EXPERIMENTALLY CAUSED TO THE ANGLE OF THE MANDIBLE OF 63 FEMALE WISTAR RATS. TWENTY ONE OF THE ANIMALS COMPOSED THE CONTROL GROUP. BENZOIC ESTRADIOL WAS ADMINISTERED INTRAMUSCULARY TO ANOTHERGROUP CONSISTED OF 21 ANIMALS AND OVARIECTOMY WAS PERFORMED TO ALL 21 ANIMALS OF THE THIRD GROUP, FOUR WEEKS BEFORE THE FRACTURES' DAY. THE STUDY METHOD USEDCOMPRISED: 1) RADIOLOGICAL EVALUATION OF THE HISTOLOGICALLY FIXED FRACTURED AREA OF THE MANDIBLE, 2) HISTOLOGICAL EXAMINATION OF THE SAME AREA, 3) BLOOD ESTRADIOL MEASUREMENT USING RIA METHODS 4) BODY WEIGHT MEASUREMENT IN VARIOUS STAGES OF THE EXPERIMENT. THE RATS WERE SACRIFICED ON THE 7TH, 14TH AND 21ST POST-FRACTURE DAY CONSEQUENTLY. WE CONCLUDE THAT: 1) BENZOIC ESTRADIOL WHEN ADMINISTERED BY THE METHOD WHICH WAS USED IN THE PRESENT STUDY IS POSITIVELY INFLUENCES THE HEALING PROCESS OF MANDIBULAR FRACTURES IN YOUNG FEMALE WISTAR RATS. HEALINGIS ALSO INFLUENCED BY THE EXACT SITE TO THE FRACTURE LINE AS FAR AS ITS LINE OF DIRECTION IS CONCERNED; THEY ARE NOT HOWEVER INFLUENCED BY THE TEETH POSITION, 3)OVARIECTOMY INCREASES BODY WEIGHT WHEREAS ESTROGENS ADMINISTRATION RESULTS IN ITS LOSS.

Grantor dc:publisher

Aristotle University Of Thessaloniki (AUTH)

Year dc:date

1988

Authors dc:creator

• Βαχτσεβάνος, Κωνσταντίνος
• Vahtsevanos, Konstantinos

• ΒΕΝΖΟΙΚΗ ΟΙΣΤΡΑΔΙΟΛΗ
• Κατάγματα
• Κάτω γνάθος
• Οιστρογόνα
• Οστική επούλωση
• ΠΩΡΟΣ
• Bone regeneration
• CALLUS
• Estradiol
• ESTRADIOL BENZOATE
• Estrogens
• Fractures
• MANDIBULARFRACTURES
• Ιατρική και Επιστήμες Υγείας
• Κλινική Ιατρική
• Medical and Health Sciences
• Clinical Medicine

Language dc:language

gre

Identifier

10.12681/eadd/1433

OAI identifier oai:identifier

oai:10442/1433