ΜΕΛΕΤΗ ΤΩΝ ΑΝΤΙΓΟΝΩΝ ΙΣΤΟΣΥΜΒΑΤΟΤΗΤΟΣ (HLA) ΣΤΟ ΣΥΝΔΡΟΜΟ ΑΔΑΜΑΝΤΙΑΔΗ-BEHCET

50 PATIENTS AND 512 HEALTHY CONTROL PERSONS WERE TESTED FOR THE FREQUENCY OF 35 HLA ANTIGENS (HLA-A, B, DR). THE ANTIGENS DETERMINATION WAS PERFORMED BY MEANS OF TERASAKI'S LYMPHOCYTOTOXICITY TECHNIQUE. AN INCREASED INCIDENCE OF HLA-B5 ANTIGEN WAS FOUND (74% IN THE PATIENTS, COMPARED TO 30% IN THE HEALTHY CONTROL POPULATION). THIS DIFFERENCE WAS STATISTICALLY HIGHLY SIGNIFICANT, P < 0,0001). THESE RESULTS LEADS TO THE CONCLUSION THAT POSSIBLY THERE IS A GENETIC BASIS WHICH PREDETERMINES THE SUSCEPTIBILITY OF ADAMANDIADES-BEHCET'S DISEASE AND ALSO THAT THE HLA-B5 ANTIGEN CONSTITUTES THE GENETIC MARKER OF THIS DISEASE.

Grantor dc:publisher

National and Kapodistrian University of Athens

Year dc:date

1985

Authors dc:creator

• Kapellou, Polyxeni
• Καπέλλου, Πολυξένη

• Ανοσολογία
• ADAMANDIADES-BEHCET DISEASE
• HLA antigens
• Ιατρική και Επιστήμες Υγείας
• Κλινική Ιατρική
• Medical and Health Sciences
• Clinical Medicine

Language dc:language

gre

Identifier

10.12681/eadd/0413

OAI identifier oai:identifier

oai:10442/0413