ΣΥΜΒΟΛΗ ΣΤΗ ΜΕΛΕΤΗ ΤΟΥ ΜΕΤΑΒΟΛΙΣΜΟΥ ΤΟΥ ΟΣΤΙΚΟΥ ΚΟΛΛΑΓΟΝΟΥ ΚΑΙ ΤΗΣ ΟΣΤΙΚΗΣ ΕΝΑΛΛΑΓΗΣ ΣΤΗ V.COOLEY ΔΙΑ ΤΟΥ ΠΡΟΣΔΙΟΡΙΣΜΟΥ ΤΗΣ ΥΔΡΟΞΥΠΡΟΛΙΝΗΣ ΟΥΡΩΝ

IN THE PRESENT STUDY, THE AMOUNT OF TOTAL HYDROXYPROLINE EXCRETED IN 24 HR/M2 URINE SAMPLES WAS MEASURED. THE SUBJECTS WERE PATIENTS STRICKEN WITH COOLEY'S ANEMIA (THALASSEMIA MAJOR). EACH SHOWED THE CHARACTERISTIC BONE CHANGES KNOWN AS OSTEOPOROSIS . THE PURPOSE OF THIS STUDY WAS TO RESEARCH THE METABOLISM OF BONECOLLAGEN AND ITS PROCESS OF TURNOVER. THE AMOUNT OF TOTAL HYDROXYPROLINE EXCRETED IN THE URINE SAMPLES/24HRS/M2 DETERMINED USING THE GOVERDE AND VEENCAMP RESIN METHOD. FOR THIS COMPARATIVE STUDY FIFTY PATIENTS WITH THALASSEMIA MAJOR WERE USED. OF THESE FIFTY, FORTY WERE IN THE 5-12 YRS, AGE GROUP, AND TEN WERE IN THE 22-58 YRS, AGE GROUP. THE AMOUNT OF TOTAL HYDROXYPROLINE EXCRETED IN THE URINE OF THE PATIENTS WAS THEN COMPARED TO THAT OF FIFTY SUBJECTS (CONTROL GROUP)IN GOOD HEALTH OF WHICH FORTY WERE IN THE 6-12 YRS AGE GROUP, AND THE REMAINING TEN WERE IN THE 22-57 YRS AGE GROUP. (SHORTENED)

Grantor dc:publisher

National and Kapodistrian University of Athens

Year dc:date

1986

Author dc:creator

• Λαουτάρης, Νικόλαος

• Αναιμία
• Θαλασσαιμία
• Κολλαγόνο
• ΟΣΤΙΚΟ
• Υδροξυπρολίνη
• Anaemia
• Collagen
• COOLEY
• Hydroxyproline
• Thalassemia
• Ιατρική και Επιστήμες Υγείας
• Κλινική Ιατρική
• Medical and Health Sciences
• Clinical Medicine

Language dc:language

gre

Identifier

10.12681/eadd/0366

OAI identifier oai:identifier

oai:10442/0366