ΣΥΓΚΡΙΤΙΚΗ ΜΕΛΕΤΗ ΧΗΜΕΙΟΑΝΟΣΟΘΕΡΑΠΕΙΑΣ ΚΑΙ ΧΗΜΕΙΟΘΕΡΑΠΕΙΑΣ ΣΕ ΠΡΟΧΩΡΗΜΕΝΟ ΚΑΡΚΙΝΟ ΟΥΡΟΔΟΧΟΥ ΚΥΣΤΕΩΣ

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

Grantor dc:publisher

National and Kapodistrian University of Athens

Year dc:date

1985

Authors dc:creator

• Kioupkiolis, Georgios
• Κιουπκιολής, Γεώργιος

• ΚΑΡΚΙΝΟΣ ΟΥΡΟΔΟΥΧΟΥ
• ΧΗΜΕΙΟΑΝΟΣΟΘΕΡΑΠΕΙΑ
• Χημειοθεραπεία
• ADVANCED BLADDER TUMOR
• CHEMIOIMMUNOTHERAPY
• CHEMIOTHERAPY
• Ιατρική και Επιστήμες Υγείας
• Κλινική Ιατρική
• Medical and Health Sciences
• Clinical Medicine

Language dc:language

gre

Identifier

10.12681/eadd/0344

OAI identifier oai:identifier

oai:10442/0344