Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Levamisole"”.
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Can levamisole upregulate the equine cell mediated immune response in vitro?
… with Sarcocystis neurona in mouse models. Levamisole has been proposed as an adjunctive therapy for EPM to upregulate the cell-mediated immune response based on positive results in other species, but there are very limited studies in equids. We hypothesized that levamisole will upregulate …
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The Effects of Levamisole, CORYNEBACTERIUM PARVUM, and Unblocked Lymphocytes on Mice Injected with Herpes Virus Type 2-transformed Cells
… therapy. Mice in group 3 received 200 μgm of levamisole, a non-specific immune stimulator. Group 4 mice were given 300 μgm of heat and formalin killed Corynebacterium parvum which is known to non specifically stimulate macrophage populations. Mice in group 5 received unblocked lymphocytes at a …
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Identification and characterization novel of cystine-loop ligand- gated chloride channels from Dirofilaria immitis: pharmacological analysis and novel compound screening
… novel derivatives of the antiparasitic drug levamisole were tested on ACC receptors to determine if any modifications enhanced levamisole action. D. immitis UNC-49B assembled as a homomeric channel and exhibited an EC50 of 5mM for GABA. UNC-49B also formed a functional channel with UNC-49C, …
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A comparative study of gastrointenstinal nematode infection in traditional and commercial chickens and efforts of anthelminthic treatment on production
… was observed with one group treated with Levamisole (25% m/v) and the other group a non-treated control. The mean weight of the two groups at the end of the 15 weeks study were, 623±574 g in the untreated control group and 812.8±51.4g in the treated group. There was a strong negative …
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A comparative study of gastrointenstinal nematode infection in traditional and commercial chickens and efforts of anthelminthic treatment on production
… was observed with one group treated with Levamisole (25% m/v) and the other group a non-treated control. The mean weight of the two groups at the end of the 15 weeks study were, 623±574 g in the untreated control group and 812.8±51.4g in the treated group. There was a strong negative …
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Investigation into potential Dirofilaria immitis drug targets through rational anthelmintic synthesis and design
… imidazole-4-acetic acid like compounds, levamisole derivatives, and a levamisole dimer. Compounds 8-15 were tested on the Hco-ACC-2 receptor using electrophysiological techniques and all demonstrated various degrees of receptor activation. Compound 13, which had the highest response, was …
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ΣΥΓΚΡΙΤΙΚΗ ΜΕΛΕΤΗ ΧΗΜΕΙΟΑΝΟΣΟΘΕΡΑΠΕΙΑΣ ΚΑΙ ΧΗΜΕΙΟΘΕΡΑΠΕΙΑΣ ΣΕ ΠΡΟΧΩΡΗΜΕΝΟ ΚΑΡΚΙΝΟ ΟΥΡΟΔΟΧΟΥ ΚΥΣΤΕΩΣ
… 50 MG/M2 IN ROTATING EVERY 3 WEEKS AND LEVAMISOLE 50 MG X 3 PER OS ON CRITICAL PERIOD AT 11TH, 12TH A 13TH DAY OF THE COURSE. THE SECOND GROUP WAS TREATED BY 5 FLU AND ADRIAMYCIN IN THE SAME DOSE AND ROTATING AS THE FIRST GROUP. THE FOLLOW UP OF THE PATIENTS WAS MADE EVERY 3 MONTHS. THE …
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Investigations into the use of continuous low-level medication for the control of helminths in the ruminant
… experiments, the anthelmintic activities of levamisole (s-(-)-2,3,5,6-tetrahydro-6-phenylimidazo (2,1-b) thiazole), febantel (N-(2-(2,3-bis-(methoxycarbonyl)-guanidino)-5-(phenyl-thio)-phenyl)-2-methoxy-acetamide) and briefly oxfendazole (5-(phenylsulfinyl)-IH-benzimidazol-2yl) carbamate) …
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The effect of application of the FAMACHA© system on selected production parameters in sheep
… 4 and 5 (overtly anaemic) were treated with levamisole HCl 2,5% (Nemasol NF, Intervet) (ii) Strategically dosed (STRAT) group, blanket treated every six weeks with levamisole HCl 2,5% (Nemasol NF, Intervet) (iii) Suppressively dosed (SUPPR) group, blanket treated at the same intervals with …
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Rho GTPase Signaling Modulates Neurotransmission in Caenorhabditis elegans
… are hypersensitive to the cholinergic agonist levamisole, without any obvious changes in synaptic structure based on the localization of fluorescence-tagged synaptobrevin. These results suggest that the UNC-73 RhoGEF2 isoforms may modulate synaptic strength and cholinergic signaling at the …
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Stability evaluation of selected anthelmintic macrocyclic lactone compounds and formulations
… from different chemical classes (e.g. levamisole and closantel). ML formulations with a single active pharmaceutical ingredient (API) are slightly unstable, due to their sensitivity towards pH, light and oxidation. However, formulations containing a combination of MLs and other APIs …
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Haemonchus contortus Infections in Alpacas and Sheep
… dewormed orally with a cocktail of fenbendazole, levamisole, and ivermectin. Haemonchus contortus infective larvae were administered orally to alpacas and rams in the following groups:1) 20,000 larvae as a single dose (bolus, n=6 both alpacas and sheep), 2) 20,000 larvae in daily doses of 4,000 …