Το ηωσινόφιλο κοκκίωμα των οστών: από ορθοπεδική άποψη

THIRTY FIVE CASES OF EOSINOPHILIC GRANULOMA OF BONE WHICH WERE TREATED IN THE ORTHOPAEDIC CLINICS OF ASCLIPIION HOSPITAL DURING THE LAST 20 YEARS, HISTOLOGICALLY CONFIRMED, WERE REVIEWED. THE RARITY OF THE DISEASE WAS CONFIRMED BECAUSE ITS FREQUENCY WAS FOUND ONLY 1% IN RELATION TO THE OTHER ORTHOPAEDIC DISEASES TREATED IN OUR HOSPITAL. MOST OF THE CASES CONCERNED CHILDHOOD AND ADOLESCENCE, BELOW 20 YEARS OF AGE (71%) AND THE DISEASE SHOWED AN INCREASED FREQUENCY TO THE MALES IN RELATION TO FEMALES (4:1). THERE WAS A CLEAR SUPERIORITY OF THE SOLITARY EOSINOPHILIC GRANULOMA IN RELATION TO THE MULTIPLE (2,5:1). THE MOST FREQUENT SYMPTOM WAS THE LOCAL PAIN, WHICH WAS OBSERVED IN MOST CASES (32 CASES). IN MANY CASES THE RADIOLOGICAL EVIDENCE WAS NOT CHARACTERISTIC FOR THE DISEASE AND DIFFERENTIAL DIAGNOSTIC PROBLEMS WERE CREATED WITH TUMORS OR INFECTIONS OF BONES. THE ONLY LABORATORY FINDING WHICH WAS FREQUENTLY OBSERVED (60%) WAS THE INCREASE OF THE SEDIMENTATION RATE; ANAEMIA AND LEUCOCYTOSIS WERE RARE AND EOSINOPHILIA IN PERIPHERAL BLOOD WAS FOUND ONLY IN 5 CASES. ALL THE BIOCHEMICAL EXAMINATIONS WERE NORMAL. ELECTROPHORESIS OF PROTEINS OF PLASMA WAS CARRIED OUT IN A CONSIDERATION NUMBER OF CASES (14 CASES). IN 8 OF THEM A DISTURBANCE OF A2 AND G GLOBULIN WAS OBSERVED AND NO RELATION OF THIS FINDING TO THE SEVERITY OF THE DISEASE WAS PROOVED. CURATTAGE OF THE AFFECTED AREAS WAS APPLIED IN 25 CASES AND IN 6 OF THEM WERE COMBINED WITH RADIOTHERAPY, SIMPLE BIOPSY FOLLOWED BY RADIOTHERAPY WAS APPLIED IN 6 CASES. IN MANY CASES OF MULTIPLELOCALIZATIONS AND NEW RELAPSES, SIMPLE ATTENDANCE OR LOCAL RADIOTHERAPY WAS APPLIED WITH GOOD USUALLY FINAL RESULT. THE FOLLOW- UP IN 28 CASES ASCERTAINED THAT THE PROGNOSIS, IN WHAT IT CONCERNS SOLITARY EOSINOPHILIC GRANULOMA OF BONE WAS GOOD, INDEPENDENTLY FROM THE TREATMENT. IN THE CASES OF MULTIPLE EOSINOPHILIC GRANULOMA, RELAPSES WERE FREQUENTLY OBSERVED (6 CASES). THE PROGNOSIS, HOWEVER, WAS GOOD, BECAUSE EVEN IN THE 4 CASES, IN WHICH RELAPSES FREQUENTLY OCCURED, NO TRANSITION TO OTHER SYNDROMS OF HISTIOCYTOSIS X, WAS OBSERVED NEITHER CLINICALLY NOR HISTOLOGICALLY AFTER BIOPSY IN NEW LOCALIZATIONS. FINALLY ALL RECHECKED PATIENTS ARE SYMPTOMS FREE EXCEPT ONE WITH RECENT RELAPSE.

Grantor dc:publisher

National and Kapodistrian University of Athens

Year dc:date

1982

Author dc:creator

• Σκουτέρης, Γεώργιος-Ιωάννης

• Ηωσινόφιλο κοκκίωμα των οστών
• ΙΣΤΙΟΚΥΤΤΑΡΩΣΗ
• Eosinophilic granuloma of bone
• Histiocytosis
• Ιατρική και Επιστήμες Υγείας
• Κλινική Ιατρική
• Medical and Health Sciences
• Clinical Medicine

Language dc:language

gre

Identifier

10.12681/eadd/0332

OAI identifier oai:identifier

oai:10442/0332