ΣΥΜΒΟΛΗ ΣΤΗΝ ΜΕΛΕΤΗ ΤΩΝ HLA-A, B, C ΚΑΙ DR ΑΝΤΙΓΟΝΩΝ ΣΤΙΣ ΥΠΟΤΡΟΠΙΑΖΟΥΣΕΣ ΑΦΘΕΣ

A STUDY OF THE FREQUENCY OF HLA-A1B1C AND DR ANTIGEΝS WAS PERFORMED IN 106 GREEK PATIENTS AFFECTED FROM RECURRENT ORAL ULCERATION (ROU) AND 120 MATCHED CONTROLS OF THE SAME NATIONALITY. THIS INVESTIGATION REVEALED THAT HLA-DRS ANTIGEN IS MORE FREQUENT IN PATIENTS (PC < 0,01) AND THUS IT MAY BE CONSIDERED AS A GENETIC MARKER OF THE DISEASE IN GREEK POPULATION. STATISTICALLY INCREASED WERE ALSO FOUND HLA-A28 (PC < 0,05) AND HLA-CW2 (PC <0,05) BUT HLA-DR4 WAS FOUNDSTATISTICALLY SIGNIFICANT DECREASED (PC < 0,05) IN PATIENTS WITH ROU. AS A GENERAL APPROACH WE MAY POSTULATE THAT GENETIC FACTORS CLOSELY RELATED WITH HLA SYSTEM PLAY A RATHER IMPORTANT ROLE IN THE DEVELOPMENT OF RECURRENT ORAL ULCERATION.

Grantor dc:publisher

Aristotle University Of Thessaloniki (AUTH)

Year dc:date

1986

Authors dc:creator

• Αλμπανίδου-Φαρμάκη, Ελένη
• Albanidou-Farmaki, Eleni

• HLA-ΑΝΤΙΓΟΝΑ
• ΑΝΤΙΓΟΝΙΚΗ ΣΥΧΝΟΤΗΤΑ
• ΑΠΛΟΤΥΠΙΚΗ ΣΥΧΝΟΤΗΤΑ
• Μείζον σύστημα ιστοσυμβατότητας
• ΥΠΟΤΡΟΠΙΑΖΟΥΣΕΣ ΑΦΘΕΣ
• ANTIGEN FREQUENCY
• HLA-ANTIGENS
• MHC-MAJOR HISTOCOMPATIBILITY COMPLEX
• RECURRENT ORAL ULCERATION
• Ιατρική και Επιστήμες Υγείας
• Κλινική Ιατρική
• Medical and Health Sciences
• Clinical Medicine

Language dc:language

gre

Identifier

10.12681/eadd/0079

OAI identifier oai:identifier

oai:10442/0079