ΜΕΛΕΤΗ ΣΥΠΛΟΚΩΝ ΜΕΤΑΛΛΙΚΩΝ ΙΟΝΤΩΝ ΜΕ 5' - ΑΔΕΝΟΣΙΝΟΜΟΝΟΦΩΣΦΟΡΙΚΟ ΟΞΥ, 6-ΜΕΡΚΑΠΤΟΠΟΥΡΙΝΗ ΚΑΙ ΤΟ ΡΙΒΟΣΙΔΙΟ ΤΗΣ ΚΑΙ 8-ΑΖΑΠΟΥΡΙΝΕΣ

IN THIS THESIS THE INTERACTION OF METAL IONS WITH ADENOSINE MONOPHOSPHATE, 6-MERCAPTOPURINE AND ITS RIBOSIDE - ANTICANCER DRUGS - AND 8-AZAPURINES IS INVESTIGATED. WE HAVE PREPARED THE COMPLEXES OF 5'- ADENOSINE MONOPHOSPHATE WITH MN2+, FE2+, ZN2+, PB2+, CD2+, PD2+, CE3+, PR3+, SM3+, TB3+, MO2 2+. THE METAL TO LIGAND RATIO IN ALL THESE COMPLEXES IS 1:1. WE HAVE ALSO PREPARED NINE COMPLEXES (1:1, 1:2) OF 6-MERCAPTOPURINE AND ITS RIBOSIDE WITH RU3+, RB3+, IR3+, R. WEHAVE PREPARED THE COMPLEXES OF ZN2+, PT2+ WITH 8-AZAADENINE, CU2+, PD2+, AU3+WITH 8-AZAGUANINE AND CO2+, AU3+, AU+ WITH 8-AZAHYPOXANTHINE. ALL THESE COMPLEXES HAVE BEEN STUDIED WITH INTRACED SPECTROSCOPY, DIFFUSE REFLECTANCE, FLUORESCENCE, NUCLEAR MAGNETIC RESONANCE AND MOSSBAUER SPECTROSCOPY, MAGNETIC SUSCEPTIBILITY AND CONDUCTIVITY MEASUREMENTS, IN ORDER TO FIND THE POSITION OF THE LIGAND TO WHICH THE METAL IS ATTACHED.

Grantor dc:publisher

National and Kapodistrian University of Athens

Year dc:date

1986

Authors dc:creator

• Grigoratou, Andriani
• Γρηγοράτου, Ανδριανή

• 5' ΑΝΔΕΝΟΣΙΝΟΜΟΝΟΦΩΣΦΟΡΙΚΟ ΟΞΥ
• 6 - Μερκαπτοπουρίνη
• 8-ΑΖΑΑΔΕΝΙΝΗ
• 8-ΑΖΑΓΟΥΑΝΙΝΗ
• 8-ΑΖΑΠΟΥΡΙΝΕΣ
• 8-ΑΖΑΥΠΟΞΑΝΘΙΝΗ
• ΡΙΒΟΣΙΔΙΟ ΤΗΣ 6-ΜΕΡΚΑΠΤΟΠΟΥΡΙΝΗΣ
• ΣΥΜΠΛΟΚΑ ΜΕΤΑΛΛΙΚΩΝ ΙΟΝΤΩΝ
• 6 - Mercaptopurine
• 6-MERCAPTOPURINE RIBOSIDE
• 8-AZAADENINE
• 8-AZAGUANINE
• 8-AZAHYPOXANTHINE
• 8-AZAPURINES
• METAL IONS COMPLEXES
• Φυσικές Επιστήμες
• Χημεία
• Natural Sciences
• Chemical Sciences

Language dc:language

gre

Identifier

10.12681/eadd/0037

OAI identifier oai:identifier

oai:10442/0037